Evaluation of Clinico-Pathological Characteristics of Oral Squamous Carcinoma in Different Age Groups in a 10-Year Period

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RAZAVI SEYED MOHAMMAD; Khalesi Saeede

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Journal: Journal of Isfahan Dental School Year:2019 | Volume:15 | Issue:2 Page(s): 156-163

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Title

Evaluation of Clinico-Pathological Characteristics of Oral Squamous Carcinoma in Different Age Groups in a 10-Year Period

Author(s)

RAZAVI SEYED MOHAMMAD | Khalesi Saeede | Issue Writer Certificate

Keywords

Oral cancerQ2

PathologyQ1

Squamous cell carcinomaQ2

Abstract

Introduction: Over 95% of Oral cancers are Squamous cell carcinomas (SCC). The prevalence of oral SCC in subjects < 40 years of age has been reported to be 0. 4‒ 3. 9% of all the subjects with this lesion. The number of young patients with this malignant tumor has increased in recent years. The present study was undertaken to evaluate the clinicopathological parameters of OSCC in patients in different age groups, referring to Isfahan Faculty of Dentistry. Materials & Methods: In this retrospective, cross-sectional study, we reviewed demographic data, clinical features and histopathological parameters of 80 OSCC cases in different age groups from the Archives of the Oral Pathology Department, Isfahan Faculty of Dentistry. The histopathological parameters and malignant tumor grades were evaluated by two oral pathologists. Data were analyzed with SPSS 22, using chi-squared and Mann-Whitney tests (α = 0. 05). Results: Of all the cases evaluated, 42 (52. 5%) were female and 38 (47. 5%) were male, with a female-to-male ratio of 1. 1. Alveolar mucosa with 31 (38. 8%) cases was the most common site of involvement in all the age groups. The most prevalent clinical feature of OSCC in the patients was exophytic lesion. Well-differentiated (grade 1) OSCC was the most common subtype of OSCC in all the age groups. There was no significant difference in the clinico-pathological parameters between the age groups (p value > 0. 05). Conclusion: Based on the results of the present study, there was no specific histopathological parameter between different age groups with OSCC. Despite the increase in the number of young patients with OSCC, it is still considered a specific malignant tumor in old age groups.

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APA: Copy

RAZAVI, SEYED MOHAMMAD, & Khalesi, Saeede. (2019). Evaluation of Clinico-Pathological Characteristics of Oral Squamous Carcinoma in Different Age Groups in a 10-Year Period. JOURNAL OF ISFAHAN DENTAL SCHOOL, 15(2 ), 156-163. SID. https://sid.ir/paper/126178/en

Vancouver: Copy

RAZAVI SEYED MOHAMMAD, Khalesi Saeede. Evaluation of Clinico-Pathological Characteristics of Oral Squamous Carcinoma in Different Age Groups in a 10-Year Period. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2019;15(2 ):156-163. Available from: https://sid.ir/paper/126178/en

IEEE: Copy

SEYED MOHAMMAD RAZAVI, and Saeede Khalesi, “Evaluation of Clinico-Pathological Characteristics of Oral Squamous Carcinoma in Different Age Groups in a 10-Year Period,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 15, no. 2 , pp. 156–163, 2019, [Online]. Available: https://sid.ir/paper/126178/en

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