EVALUATION OF THE VIRULENCE MARKERS OF HELICOBACTER PYLORI IN DENTAL PLAQUE OF PATIENTS WITH GASTRITIS: A PRELIMINARY STUDY

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NAVABI NADER; BAZRAFSHANI MOHAMMADREZA; TAHMASEBI ARASHLOO MEHRNAZ; HOSEINI FATEMEHSADAT

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Journal: Journal of Isfahan Dental School Year:2014 | Volume:10 | Issue:6 Page(s): 468-476

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Title

EVALUATION OF THE VIRULENCE MARKERS OF HELICOBACTER PYLORI IN DENTAL PLAQUE OF PATIENTS WITH GASTRITIS: A PRELIMINARY STUDY

Author(s)

NAVABI NADER | BAZRAFSHANI MOHAMMADREZA | TAHMASEBI ARASHLOO MEHRNAZ | HOSEINI FATEMEHSADAT | Issue Writer Certificate

Keywords

DENTAL PLAQUEQ3

GASTRITISQ3

HELICOBACTER PYLORIQ2

Abstract

Introduction: HELICOBACTER PYLORI (H. pylori) is a gram-negative motile spiral-shaped bacterium that is strongly associated with gastroduodenal diseases. Recently, DENTAL PLAQUE has been implicated as a possible source of H. pylori infection. Two important virulence factors that are expressed by the alleles of vac A (vacuolating toxin) and cag A (cytotoxin-associated gene A) have been identified. The aim of this study was to determine whether or not virulence factor genes vac A and cag A are present in H. pylori retrieved from DENTAL PLAQUE in patients with GASTRITIS.Materials and Methods: In this cross-sectional study, DENTAL PLAQUE specimens from 42 patients with GASTRITIS, referring to the endoscopy section of a hospital, were subjected to polymerase chain reaction (PCR) assay to detect the presence of cag A and vac A genotypes of H. pylori.Results: DNA from H. pylori was detected in 4 DENTAL PLAQUE samples. All these 4 samples were vac A-positive and 2 samples were positive for both vac A and cag A genotypes.Conclusion: The pathogenic strains isolated from the DENTAL PLAQUE in the present study suggest it is possible for more than one virulence factor of H. pylori to exist in some patients. However, further studies are required to confirm this finding.

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APA: Copy

NAVABI, NADER, BAZRAFSHANI, MOHAMMADREZA, TAHMASEBI ARASHLOO, MEHRNAZ, & HOSEINI, FATEMEHSADAT. (2014). EVALUATION OF THE VIRULENCE MARKERS OF HELICOBACTER PYLORI IN DENTAL PLAQUE OF PATIENTS WITH GASTRITIS: A PRELIMINARY STUDY. JOURNAL OF ISFAHAN DENTAL SCHOOL, 10(6), 468-476. SID. https://sid.ir/paper/126400/en

Vancouver: Copy

NAVABI NADER, BAZRAFSHANI MOHAMMADREZA, TAHMASEBI ARASHLOO MEHRNAZ, HOSEINI FATEMEHSADAT. EVALUATION OF THE VIRULENCE MARKERS OF HELICOBACTER PYLORI IN DENTAL PLAQUE OF PATIENTS WITH GASTRITIS: A PRELIMINARY STUDY. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2014;10(6):468-476. Available from: https://sid.ir/paper/126400/en

IEEE: Copy

NADER NAVABI, MOHAMMADREZA BAZRAFSHANI, MEHRNAZ TAHMASEBI ARASHLOO, and FATEMEHSADAT HOSEINI, “EVALUATION OF THE VIRULENCE MARKERS OF HELICOBACTER PYLORI IN DENTAL PLAQUE OF PATIENTS WITH GASTRITIS: A PRELIMINARY STUDY,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 10, no. 6, pp. 468–476, 2014, [Online]. Available: https://sid.ir/paper/126400/en

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