NITRIC OXIDE CONCENTRATIONS IN SALIVA IN RELATION TO CARIES; EXPERIENCE IN 6-12 YEARS OLD CHILDREN

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JAVADINEZHAD SH.; TALEBI MORTEZA; ASLANI GOLNAZ

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Journal: JOURNAL OF ISFAHAN DENTAL SCHOOL Year:2007 | Volume:3 | Issue:2 Page(s): 71-75

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Title

NITRIC OXIDE CONCENTRATIONS IN SALIVA IN RELATION TO CARIES; EXPERIENCE IN 6-12 YEARS OLD CHILDREN

Author(s)

JAVADINEZHAD SH. | TALEBI MORTEZA | ASLANI GOLNAZ | Issue Writer Certificate

Keywords

NITRIC OXIDEQ3

SALIVAQ2

CARIESQ3

Abstract

Introduction: Recently, there is a growing interest in the role of nitrate and nitrites in protecting against oral and gastrointestinal diseases. In human, ingested nitrate absorbs into the blood and concentrates in the SALIVAry glands rapidly changes to nitrite. Nitrite may then be acidified through encounter with the plaque micro flora. The acidification of nitrite produces a mixture of nitrogen oxides as well as nitrous acid. Nitrous acid will spontaneously decompose to produce NITRIC OXIDE (NO). NO participates in the nonspecific defense mechanisms of the oral cavity to prevent bacteria from overgrowing. The aim of the study was to determine the correlation of NITRIC OXIDE with dental CARIES in children in mixed dentition period.Methods and Materials: 3 ten-member groups of children aged 6–12 years old were selected according to decayed and filled surfaces (dfs); with dfs < 1, 1< dfs < 5, and 5 < dfs > 10. A 2ml sample of SALIVA of each child was taken and transferred to laboratory, where by using the chromatograph unit, NO concentration was measured. Data was analyzed by ANOVA and t-tests.Results: Based on the laboratory findings, NO concentration in dfs < 1 group showed significant difference with other groups; but there was no significant difference of the NO concentration in groups with 5 < dfs < 10 and dfs > 10.Conclusion: The NO levels were higher in high dfs groups. NO production might be a host defense mechanism when dental CARIES increases.

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APA: Copy

JAVADINEZHAD, SH., TALEBI, MORTEZA, & ASLANI, GOLNAZ. (2007). NITRIC OXIDE CONCENTRATIONS IN SALIVA IN RELATION TO CARIES; EXPERIENCE IN 6-12 YEARS OLD CHILDREN. JOURNAL OF ISFAHAN DENTAL SCHOOL, 3(2), 71-75. SID. https://sid.ir/paper/126612/en

Vancouver: Copy

JAVADINEZHAD SH., TALEBI MORTEZA, ASLANI GOLNAZ. NITRIC OXIDE CONCENTRATIONS IN SALIVA IN RELATION TO CARIES; EXPERIENCE IN 6-12 YEARS OLD CHILDREN. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2007;3(2):71-75. Available from: https://sid.ir/paper/126612/en

IEEE: Copy

SH. JAVADINEZHAD, MORTEZA TALEBI, and GOLNAZ ASLANI, “NITRIC OXIDE CONCENTRATIONS IN SALIVA IN RELATION TO CARIES; EXPERIENCE IN 6-12 YEARS OLD CHILDREN,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 3, no. 2, pp. 71–75, 2007, [Online]. Available: https://sid.ir/paper/126612/en

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