DOSE ENHANCEMENT DUE TO INJECTION OF 79AU, 64GA, 26FE AND 22TI NANOPARTICLES INTO TUMOR DURING HDR- 192IR BRACHYTHERAPY TREATMENT: MONTE CARLO STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZABIHZADEH MANSOUR; AREFIAN SEYEDEH SAHAR; SHAMS NASIM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Scientific Medical Journal Year:2013 | Volume:12 | Issue:3 (84) Page(s): 313-324

Download Full-Text

Persian Verion

View:

1,036

Download:

Cites:

Information Journal Paper

Title

DOSE ENHANCEMENT DUE TO INJECTION OF 79AU, 64GA, 26FE AND 22TI NANOPARTICLES INTO TUMOR DURING HDR- 192IR BRACHYTHERAPY TREATMENT: MONTE CARLO STUDY

Author(s)

ZABIHZADEH MANSOUR | AREFIAN SEYEDEH SAHAR | SHAMS NASIM | Issue Writer Certificate

Keywords

DOSE ENHANCEMENT FACTORQ2

192IR BRACHYTHERAPY SOURCEQ2

MONTE CARLO SIMULATIONQ2

NANOPARTICLESQ2

Abstract

Background and Objective: On the base of photon interactions with material, increase of atomic number and decrease of emitted photon energy increases photoelectric absorption. In the current study, the DOSE ENHANCEMENT FACTOR (DEF) of loaded tumor with NANOPARTICLES (NPs) was studied using 192Ir HDR brachytherapy source.Subjects and Methods: Monte Carlo calculations were performed with MCNP4C code to determine the DEF from 192Ir source. The NPs-water mixture model was simulated. Uniform distribution of NPs into the tumor volume located 1.5 cm from center of source centered in the water phantom with 7, 18 and 30 mgr/gr concentrations of 79Au, 64Ga, 26Fe and 22Ti, was considered.Result: DEF of 1.049, 1.122, 1.201 and 1.033, 1.083 and 1.136 were estimated for 79Au and 64Gd with concentrations of 7, 18 and 30 mgr/gr, respectively. Increasing of tumor doses was not significant due to loading of 26Fe and 22Ti. Increase the radial distance of source from the tumor (from 1.5 to 5 cm) increases the DEF (up to 22.3%).Conclusion: Our data predicate that loading of tumor with high-Z NPs such as gold NPs increase the absorbed dose of tumor irradiated to 192Ir HDR brachytherapy source due to increase of photoelectric interactions. Increase of atomic number and concentration of NPs and radial distance of tumor from the source increase DEF. Loading of the tumor volume with NPs during radiation therapy improves therapeutic ratio.

Cites

No record.

References

No record.

Cite

APA: Copy

ZABIHZADEH, MANSOUR, AREFIAN, SEYEDEH SAHAR, & SHAMS, NASIM. (2013). DOSE ENHANCEMENT DUE TO INJECTION OF ⁷⁹AU, ⁶⁴GA, ²⁶FE AND ²²TI NANOPARTICLES INTO TUMOR DURING HDR- ¹⁹²IR BRACHYTHERAPY TREATMENT: MONTE CARLO STUDY. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 12(3 (84)), 313-324. SID. https://sid.ir/paper/12764/en

Vancouver: Copy

ZABIHZADEH MANSOUR, AREFIAN SEYEDEH SAHAR, SHAMS NASIM. DOSE ENHANCEMENT DUE TO INJECTION OF ⁷⁹AU, ⁶⁴GA, ²⁶FE AND ²²TI NANOPARTICLES INTO TUMOR DURING HDR- ¹⁹²IR BRACHYTHERAPY TREATMENT: MONTE CARLO STUDY. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2013;12(3 (84)):313-324. Available from: https://sid.ir/paper/12764/en

IEEE: Copy

MANSOUR ZABIHZADEH, SEYEDEH SAHAR AREFIAN, and NASIM SHAMS, “DOSE ENHANCEMENT DUE TO INJECTION OF ⁷⁹AU, ⁶⁴GA, ²⁶FE AND ²²TI NANOPARTICLES INTO TUMOR DURING HDR- ¹⁹²IR BRACHYTHERAPY TREATMENT: MONTE CARLO STUDY,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 12, no. 3 (84), pp. 313–324, 2013, [Online]. Available: https://sid.ir/paper/12764/en

Related Journal Papers