Antinociceptive effects of Artemisia persica boiss essential oil in male mice using formalin and tail immersion tests

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ebrahimi Tayebeh; SETORKI MAHBUBEH; Dastanpour Nasrollah

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2019 | Volume:12 | Issue:11 Page(s): 23-31

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

402

Download:

Cites:

Information Journal Paper

Title

Antinociceptive effects of Artemisia persica boiss essential oil in male mice using formalin and tail immersion tests

Author(s)

Ebrahimi Tayebeh | SETORKI MAHBUBEH | Dastanpour Nasrollah | Issue Writer Certificate

Keywords

ArtemisiaQ1

Pain MeasurementQ1

PainQ1

Abstract

Background and Objectives: Artemisia species have long been used to relieve neurological and visceral Pains. A. persica Boiss is one of the species in the genus Artemisia, which has antioxidant, antimicrobial, and cytotoxic effects. The aim of this study was to investigate the analgesic effects of A. persica Boiss essential oil in male mice. Methods: In this experimental study, the analgesic effect of A. persica Boiss essential oil was investigated on male mice using formalin and tail immersion tests. In each test, male BALB/c mice were randomly divided into five groups of eight, including negative control (received normal saline, intraperitoneal injection), positive control (received morphine 10mg/kg, intraperitoneal injection), and intervention groups (50, 75, and 100mg/kg of A. persica Boiss essential oil, intraperitoneal injection). Data were analyzed using One way ANOVA and Duncan test. Results: Treatment of mice with A. persica essential oil at a dose of 100mg/kg significantly reduced the duration of paw licking, clopping, and lifting in the first phase of formalin test (p<0. 05) and at the doses of 50, 75, and 100mg/kg significantly reduced the duration of paw licking, clopping, and lifting in the second phase of formalin test (p<0. 05). In addition, the essential oil at the dose of 100mg/kg significantly increased the Pain response time in the tail immersion test 0 and 6 minutes after injection (p<0. 05). Conclusion: Observation of the analgesic effects of A. persica Boiss essential oil in mice can be helpful for future clinical use.

Cites

Protective Effects of Artemisia persica Essential Oil Against Pentylenetetrazol-Induced Seizure in Male Mice with Emphasizing Its Mechanism of Action

References

Cite

APA: Copy

Ebrahimi, Tayebeh, SETORKI, MAHBUBEH, & Dastanpour, Nasrollah. (2019). Antinociceptive effects of Artemisia persica boiss essential oil in male mice using formalin and tail immersion tests. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 12(11 ), 23-31. SID. https://sid.ir/paper/131858/en

Vancouver: Copy

Ebrahimi Tayebeh, SETORKI MAHBUBEH, Dastanpour Nasrollah. Antinociceptive effects of Artemisia persica boiss essential oil in male mice using formalin and tail immersion tests. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2019;12(11 ):23-31. Available from: https://sid.ir/paper/131858/en

IEEE: Copy

Tayebeh Ebrahimi, MAHBUBEH SETORKI, and Nasrollah Dastanpour, “Antinociceptive effects of Artemisia persica boiss essential oil in male mice using formalin and tail immersion tests,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 12, no. 11 , pp. 23–31, 2019, [Online]. Available: https://sid.ir/paper/131858/en

Related Journal Papers