Inhibitory Effect of Aquatic and Alcoholic Extracts of Artemisia sieberi on Growth of Candida Albicans: An In Vitro Study

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Azam Taheri Ali; GHOLAMPOUR AZIZI ISSA; HASHEMI MASOUD; Farhadi Leyla; SERVATYARI KARO; ROUHI SAMANEH

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2018 | Volume:12 | Issue:6 Page(s): 39-47

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Information Journal Paper

Title

Inhibitory Effect of Aquatic and Alcoholic Extracts of Artemisia sieberi on Growth of Candida Albicans: An In Vitro Study

Author(s)

Keywords

Aqueous and alcoholic extractsQ1

ArtemisiaQ1

Candida albicansQ1

In vitro techniquesQ1

Abstract

Background and Objectives: Candida albicans (C. albicans) as an opportunistic pathogen, can causes cutaneous and mucosal infections. Antibiotic treatments for this fungus have multiple adverse effects and cause drug resistance. In this study, the inhibitory effect of Artemisia sieberi (A. sieberi), was investigated on growth of Candida albicans. Methods: In this experimental study, Aqueous and alcoholic extracts were prepared from A. sieberi using percolation method. Using disk diffusion method, minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), were assessed to evaluate the antifungal effects of these extracts on C. albicans in vitro. Results: C. albicans, was resistant to hydroalcoholic extracts in the disk diffusion method and grew around the disks containing the extracts. The MIC of aqueous, ethanolic, and methanolic extracts, were determined to be 6250, 3125, and 6250μ g/ml, respectively, and MFC of these three extracts, were determined 12500, 6250, and 12500μ g/ml, respectively. In the MIC and MFC method, ethanolic extracts had higher antifungal activity. Conclusion: According to the results of this study, different extracts of A. sieberi affect C. albicans growth and prevent its growth. Thus, more examinations are needed to survey the composition of this plant and more extensive use in human domains.

Cites

In-vitro antibacterial effects of Artemisia extracts on clinical strains of P. aeruginosa, S. pyogenes, and oral bacteria

References

Antifungal effect of melia azedarach alcoholic and aquatic extract on Malassezia furfur

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APA: Copy

Azam Taheri, Ali, GHOLAMPOUR AZIZI, ISSA, HASHEMI, MASOUD, Farhadi, Leyla, SERVATYARI, KARO, & ROUHI, SAMANEH. (2018). Inhibitory Effect of Aquatic and Alcoholic Extracts of Artemisia sieberi on Growth of Candida Albicans: An In Vitro Study. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 12(6 ), 39-47. SID. https://sid.ir/paper/132052/en

Vancouver: Copy

Azam Taheri Ali, GHOLAMPOUR AZIZI ISSA, HASHEMI MASOUD, Farhadi Leyla, SERVATYARI KARO, ROUHI SAMANEH. Inhibitory Effect of Aquatic and Alcoholic Extracts of Artemisia sieberi on Growth of Candida Albicans: An In Vitro Study. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2018;12(6 ):39-47. Available from: https://sid.ir/paper/132052/en

IEEE: Copy

Ali Azam Taheri, ISSA GHOLAMPOUR AZIZI, MASOUD HASHEMI, Leyla Farhadi, KARO SERVATYARI, and SAMANEH ROUHI, “Inhibitory Effect of Aquatic and Alcoholic Extracts of Artemisia sieberi on Growth of Candida Albicans: An In Vitro Study,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 12, no. 6 , pp. 39–47, 2018, [Online]. Available: https://sid.ir/paper/132052/en

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