THE EFFECT OF 12-WEEK RESISTANCE TRAINING ON CARDIAC HYPERTROPHY, GLUCOSE LEVEL, INSULIN, AND INSULIN RESISTANCE INDEX IN STZ-INDUCED DIABETIC RATS

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MOHAMMADI RASOUL; MATIN HOMAEE HASAN; AZARBAYJANI MOHAMMAD ALI; BAESI KAZEM

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2017 | Volume:11 | Issue:2 Page(s): 38-45

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Title

THE EFFECT OF 12-WEEK RESISTANCE TRAINING ON CARDIAC HYPERTROPHY, GLUCOSE LEVEL, INSULIN, AND INSULIN RESISTANCE INDEX IN STZ-INDUCED DIABETIC RATS

Author(s)

MOHAMMADI RASOUL | MATIN HOMAEE HASAN | AZARBAYJANI MOHAMMAD ALI | BAESI KAZEM | Issue Writer Certificate

Keywords

RESISTANCE TRAININGQ2

DIABETES MELLITUSQ2

RATSQ2

Abstract

Background and Objectives: Type 2 diabetes is a risk factor for heart disease and has a major contribution in mortality due to cardiovascular diseases. In the present study, the effect of 12-week RESISTANCE TRAINING was investigated on cardiac hypertrophy, glucose, level, insulin, and insulin resistance index in STZ-induced diabetic RATS.Methods: A total of 16 male Wistar RATS (mean weight, 200±20g) were randomly divided into two groups of diabetic control and (N=8), diabetic resistance (N=8). The diabetic RESISTANCE TRAINING group performed a 12-week RESISTANCE TRAINING, and 48 hours after the end of the last training session, the RATS were anesthetized and euthanized. The variables of interest (body weight, heart weight, left ventricular weight, percentage of heart weight to body weight, percentage of left ventricular weight to heart weight, resting heart rate, level of glucose, insulin, and insulin resistance index), were measured. Data analysis was performed using independent samples t-test at significance level of p≤0.05.Results: There was a significant difference among mean heart weight (p=0.050), left ventricular weight (p=0.002), level of glucose (p=0/000), insulin (p=0.000), and resting heart rate (p=0.021) in the resistance diabetic group compared to the control diabetic group.Conclusion: According to the results of the present study, it seems that RESISTANCE TRAINING is an important strategy to improve the structure and function of the heart in diabetics and it can be considered as an effective intervention method.

Cites

The effect of high intensity interval training and Aloe Vera consumption on resistin and insulin resistance index in diabetic rats

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APA: Copy

MOHAMMADI, RASOUL, MATIN HOMAEE, HASAN, AZARBAYJANI, MOHAMMAD ALI, & BAESI, KAZEM. (2017). THE EFFECT OF 12-WEEK RESISTANCE TRAINING ON CARDIAC HYPERTROPHY, GLUCOSE LEVEL, INSULIN, AND INSULIN RESISTANCE INDEX IN STZ-INDUCED DIABETIC RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 11(2), 38-45. SID. https://sid.ir/paper/132135/en

Vancouver: Copy

MOHAMMADI RASOUL, MATIN HOMAEE HASAN, AZARBAYJANI MOHAMMAD ALI, BAESI KAZEM. THE EFFECT OF 12-WEEK RESISTANCE TRAINING ON CARDIAC HYPERTROPHY, GLUCOSE LEVEL, INSULIN, AND INSULIN RESISTANCE INDEX IN STZ-INDUCED DIABETIC RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2017;11(2):38-45. Available from: https://sid.ir/paper/132135/en

IEEE: Copy

RASOUL MOHAMMADI, HASAN MATIN HOMAEE, MOHAMMAD ALI AZARBAYJANI, and KAZEM BAESI, “THE EFFECT OF 12-WEEK RESISTANCE TRAINING ON CARDIAC HYPERTROPHY, GLUCOSE LEVEL, INSULIN, AND INSULIN RESISTANCE INDEX IN STZ-INDUCED DIABETIC RATS,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 11, no. 2, pp. 38–45, 2017, [Online]. Available: https://sid.ir/paper/132135/en

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