THE EFFECT OF TWO TYPES OF EXERCISE ON SERUM CHEMERIN IN DIABETIC MALE RATS

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KHALAFI MOUSA; SHABKHIZ FATEMEH; ZOLFAGHARI MOHAMMADREZA; ZAREI YASHAR

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2016 | Volume:10 | Issue:8 Page(s): 27-35

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Title

THE EFFECT OF TWO TYPES OF EXERCISE ON SERUM CHEMERIN IN DIABETIC MALE RATS

Author(s)

KHALAFI MOUSA | SHABKHIZ FATEMEH | ZOLFAGHARI MOHAMMADREZA | ZAREI YASHAR | Issue Writer Certificate

Keywords

CHEMERIN PROTEINQ1

RATQ2

EXERCISEQ2

DIABETES MELLITUSQ2

Abstract

Background and Objectives: Chemerin is a novel adipokine, which plays a key role in the pathological process of insulin resistance and inflammation; clinical studies have shown that chemerin levels increase in diabetic patients. However, the acute effect of EXERCISE on chemerin is not known. In this research, serum changes of chemerin in diabetic male RATs were investigated in response to two types of EXERCISE.Methods: In this experimental study, 29 diabetic male RATs (age, 12 weeks; weight, 220-240g) were assigned to 5 groups, including immediately and 2 hours after high-intensity interval EXERCISE (HIIE0, HIIE2), immediately and 2 hours after moderate-intensity continuous EXERCISE (MICE0, MICE2), and control (C). Both MICE groups EXERCISE on treadmill (intensity, 60-65% vo2max) for 40 min, and both HIIE groups (with intensity of 90-95% vo2max) in 12 one-minute intervals with one-minute rest intervals. ELISA technique was used to measure serum chemerin. Data were analyzed using one-way ANOVA and post-hoc Tukey's test. The level of significance was considered at 0.05.Results: Serum chemerin levels in MICE0, MICE2 groups and HIIE2 groups, significantly increased compared to the control group (p˂0.05). However, there was no significant difference between HIIE0 group and control group (p>0.05). There was significant difference between MICE0 and HIIE2 groups with HIIE0 group (p˂0.05).Conclusion: The results of the present research showed that acute EXERCISE leads to increase in serum chemerin in diabetic male RATs.

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APA: Copy

KHALAFI, MOUSA, SHABKHIZ, FATEMEH, ZOLFAGHARI, MOHAMMADREZA, & ZAREI, YASHAR. (2016). THE EFFECT OF TWO TYPES OF EXERCISE ON SERUM CHEMERIN IN DIABETIC MALE RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 10(8), 27-35. SID. https://sid.ir/paper/132420/en

Vancouver: Copy

KHALAFI MOUSA, SHABKHIZ FATEMEH, ZOLFAGHARI MOHAMMADREZA, ZAREI YASHAR. THE EFFECT OF TWO TYPES OF EXERCISE ON SERUM CHEMERIN IN DIABETIC MALE RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2016;10(8):27-35. Available from: https://sid.ir/paper/132420/en

IEEE: Copy

MOUSA KHALAFI, FATEMEH SHABKHIZ, MOHAMMADREZA ZOLFAGHARI, and YASHAR ZAREI, “THE EFFECT OF TWO TYPES OF EXERCISE ON SERUM CHEMERIN IN DIABETIC MALE RATS,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 10, no. 8, pp. 27–35, 2016, [Online]. Available: https://sid.ir/paper/132420/en

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