Effect of Sex and Sex Hormones on SARS-COV-2: A Review Article

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Zaker Erfan; Ansariniya Hossein; Zare Fatemeh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Scientific Medical Journal Year:2023 | Volume:22 | Issue:3 Page(s): 377-389

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Effect of Sex and Sex Hormones on SARS-COV-2: A Review Article

Author(s)

Zaker Erfan | Ansariniya Hossein | Zare Fatemeh | Issue Writer Certificate

Keywords

GenderQ4

MenQ4

WomenQ4

sex hormonesQ4

SARS-CoV-2Q4

Abstract

When Men are exposed to the coronavirus infection (SARS-CoV-2), compared with Women, they will suffer from more severe consequences of this disease, leading to a higher death rate. These differences are probably due to sex-specific behaviors, genetic and hormonal factors, and sex differences in biological pathways associated with SARS-CoV-2 infection. Several socio-behavioral factors are involved in pathogenesis in Men compared to Women. However, sexual-biological differences and their effects on SARS-CoV-2 outcomes have received less scholarly attention. Sexual-biological differences between healthy populations and age- and sex-specific conditions such as pregnancy and Menopause also play a role. More extensive studies on Gender-specific differences and robust analyses are needed to determine how Gender can alter the cellular and molecular pathways associated with SARS-CoV-2. This will improve biomarker interpretation and clinical management of SARS-CoV-2 patients by facilitating a personalized medicine approach to risk stratification, prevention, and treatment. The present review summarizes the available literature on the proposed molecular and cellular markers associated with SARS-CoV-2 infection, their association with health outcomes, and any Gender-specific variation reported.

Cites

No record.

References