Clinical Manifestations and Outcomes of COVID-19 in Diabetes Mellitus People, Yazd, Iran-2021

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Mehrabbeik Akram; Mirzaei Mohsen; Askari Maryam; Sahami Mohamad Ali; Minoosepehr Mozhgan; Namiranian Nasim

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Journal Paper

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Journal: Iranian Journal of Diabetes and Obesity Year:2023 | Volume:15 | Issue:4 Page(s): 194-200

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Title

Clinical Manifestations and Outcomes of COVID-19 in Diabetes Mellitus People, Yazd, Iran-2021

Author(s)

Keywords

COVID-19Q4

DiabetesQ4

InpatientsQ4

OutcomesQ4

Abstract

Objective: Diabetes mellitus is reported to be the third most prevalent comorbidity with COVID-19, after cardio‐cerebrovascular disease and hypertension. Furthermore, Diabetes increases the likelihood of admission to the hospital and intensive care unit and death from COVID-19. The aim of the present study was to compare the clinical manifestations and Outcomes of COVID-19 in diabetic versus non-diabetic Inpatients. Materials and Methods: The medical records of 6525 patients with definitive diagnosis of COVID-19 were obtained from the reference COVID-19 diagnosis laboratory from January to July 2021 in Yazd, Iran. Patients were investigated for data on onset, clinical history, and fatality rate. COVID-19-related death was defined as positive RT-PCR in at least one of three nasal samples. Data were analysed using SPSS 24. Results: Among Inpatients, 21. 2% were diabetic. The mean ages of diabetic and non-diabetic patients were 64. 45 (±13. 87) and 52. 98 (±20. 36) years, respectively. Diabetics were more likely to be admitted to the intensive care unit (6. 8% vs. 5%, P= 0. 02) and the fatality rate was higher among them than non-diabetics (22. 6% vs. 12%, P< 0. 001). In diabetics, the mean age of non-survivors was lower than that of survivors (62. 57 vs. 70. 48, P= 0. 0001) and the frequency of death was higher among men than women (53% vs. 47. 5%, P= 0. 045). Generally, Diabetes has the strongest association with COVID-19 death (P= 0. 0001). Conclusion: Diabetic patients experience more adverse Outcomes because of COVID-19. These findings indicate the need for special attention in relation to prevention treatment against COVID-19 in patients with Diabetes.

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