The Effect of Eight Weeks of High-Intensity Interval Training with L-Cysteine Consumption on CRP and TNF-α in Heart Tissue of Young Rats with Type 2 Diabetes

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Davoudi Mana; Nouri Habashi Akbar; Baghaiee Behrouz

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Disease and Diagnosis Year:2023 | Volume:12 | Issue:4 Page(s): 187-192

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

The Effect of Eight Weeks of High-Intensity Interval Training with L-Cysteine Consumption on CRP and TNF-α in Heart Tissue of Young Rats with Type 2 Diabetes

Author(s)

Davoudi Mana | Nouri Habashi Akbar | Baghaiee Behrouz | Issue Writer Certificate

Keywords

Keywords: Type 2 diabetesQ4

InflammationQ4

High-intensity interval trainingQ4

L-cysteineQ4

Abstract

Background: This study aimed to investigate the effect of 8-weeks of High-intensity interval training (HIIT) with L-cysteine consumption on tumor necrosis factor-alpha (TNF-α) and C-reactive protein (CRP) of heart tissue in young rats with type 2 diabetes. Methods: The statistical population of the present study consisted of young (4 months) rats with type 2 diabetes. Ten rats were selected as a healthy group, and 40 rats became diabetic. Diabetic rats were randomly divided into four groups: diabetes control, diabetics with training, diabetics with supplements, and diabetics with training+supplement. Moreover, high-intensity interval exercises were performed 3 days a week for 8 weeks, and 500 micromoles of L-cysteine were administered daily. Results: The training+supplement group had significantly higher TNF-α levels compared to the diabetic control group (P=0.002). The diabetic control group (P=0.001) and training group (P=0.001) had higher TNF-α levels compared to the healthy control. The supplement group had significantly less TNF-α compared to the diabetic control group (P=0.003), while the supplement group (P=0.019) and the training+supplement group (P=0.013) had lower TNF-α levels compared to the training group. Moreover, the training+supplement group had lower CRP levels compared to the diabetic control group (P=0.001), while the diabetic control (P=0.001), exercise (P=0.002), and supplement group (P=0.031) had higher CRP levels compared to the healthy control. Moreover, the training group (P=0.038) and the supplement group (P=0.002) had lower CRP compared to the diabetic control group. Furthermore, the training+supplement group had a lower CRP level compared to the training group (P=0.03). Conclusion: HIIT along with the L-cysteine consumption reduced TNF-α and CRP in the heart tissue of diabetic rats.

Cites

No record.

References