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Information Journal Paper

Title

Relationship of Colorectal Polyps Emergence with Age and Polyp Histopathology

Pages

  91-98

Abstract

 Aims: Two-thirds of all colonic Polyps are Adenomas, which are dysplastic and have the potential for malignant transformation. This study aimed to assess the Prevalence of colorectal Polyps and its relation with patients’ age and Polyp histopathology. Instrument & Methods: This cross-sectional retrospective study was conducted on patients attending Gastroenterology and Hepatology Teaching Hospital, a major tertiary hospital in Iraq, who underwent colonoscopy for various indications from January 2020 to April 2022 using a colonoscopic and histopathologic reporting database. The eligible number of patients was 3494. Age, sex, symptoms, indications for colonoscopy, Polyp types, location, size, histopathologic types, and grading of dysplasia were collected by manually reviewing the files. The chi-square test was used for categorical data. Findings: The Polyp detection rate was 16.3%, increasing with age reaching (46.7%) at age ≥60. The Adenoma detection rate was 5.8%, with the highest (18.7%) at age ≥60, with no difference between males and females. Retention and inflammatory Polyps are the commonest findings in patients <30 years old, while most patients with Adenoma were ≥30 years old. Younger patients tended to have more distally located lesions compared with older patients with lesions at different levels; high-grade dysplastic Adenoma had more pedunculated morphology (38.6%) and their size ≥1 cm in 63% of patients. Conclusion: Increasing age is associated with an increased Prevalence of colorectal Polyps, especially Adenoma, with male predominance. Tubulovillous Adenoma and Adenoma with advanced pathology are common findings. Over 1cm pedunculated Polyps are associated with high-grade dysplasia.

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