The Effect of Eight Weeks of Resistance Training and Testosterone Enanthate Consumption on TNF-α and IL-6 Genes’ Expression in the Kidney Tissue of Female Wistar Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Molaei Khadijeh; Mirzayan Shanjani Sanaz; Gorzi Ali; Kazemzadeh Yaser; Banaeifar Abdolali

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Zahedan Journal of Research in Medical Sciences Year:2023 | Volume:25 | Issue:3 Page(s): 1-6

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

The Effect of Eight Weeks of Resistance Training and Testosterone Enanthate Consumption on TNF-α and IL-6 Genes’ Expression in the Kidney Tissue of Female Wistar Rats

Author(s)

Keywords

Resistance TrainingQ4

Testosterone EnanthateQ4

Kidney TissueQ4

Inflammatory FactorsQ4

Abstract

Objectives: This study aimed to evaluate the effect of Testosterone Enanthate anabolic steroid on the gene expression of Inflammatory Factors in the Kidney Tissue of female rats following eight weeks of Resistance Training. Methods: Twenty-one female Wistar rats weighing 200 ± 20 g, aged eight weeks, were prepared from the Iran Pasture Institute. Following a week for acclimatization, the rats were randomly divided into three groups: control (n = 7), training + placebo (n = 6), and training + Testosterone Enanthate (n = 8). Resistance Training included five days a week of climbing a 1-meter ladder with 26 stairs while bearing weights and two days of rest. In the first week, the weights were equal to 40% of the rats’ body weight. In the following weeks, the weight was increased by 20% per week. The rats were weighed two times a week. In the testosterone group, the rats were injected with 20 mg of Testosterone Enanthate thrice a week. Forty-eight hours following the last training session and testosterone injection, Kidney Tissue samples were collected to determine the gene expression of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) using real-time PCR. Results: The results showed that testosterone consumption significantly increased the gene expression of TNF-α and IL-6 in female rats undergoing testosterone and Resistance Training (P = 0.001). Conclusions: The findings of this study demonstrated that using testosterone increased Inflammatory Factors in the Kidney Tissue of female Wistar rats.

Cites

No record.

References

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops