Association of Lymphovascular Space Invasion (LVSI) with Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study

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Rafiee Azita; Mohammadizadeh Fereshteh

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Journal Paper

Paper Information

Journal: Advanced Biomedical Research Year:2023 | Volume:12 | Issue:june Page(s): 1-5

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Information Journal Paper

Title

Association of Lymphovascular Space Invasion (LVSI) with Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study

Author(s)

Rafiee Azita | Mohammadizadeh Fereshteh | Issue Writer Certificate

Keywords

Endometrial neoplasmsQ4

lymphatic metastasisQ4

myometriumQ4

neoplasm gradingQ4

neoplasm invasivenessQ4

Abstract

Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI.

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