Green tea kombucha in diabetes management: Dependent doses analysis for anti-diabetic, antioxidant, and anti-inflammatory in STZ-induced rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Humairah Ira; Darmawan Rahmad; Hassan Mohammed A.; Qurnianingsih Ema; Lukitasari Lina; Linda Linda; Prabowo Gwenny Ichsan; Utomo Budi; Mukono Indri Safitri

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medicinal and Pharmaceutical Chemistry Research Year:2026 | Volume:8 | Issue:3 Page(s): 530-544

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Green tea kombucha in diabetes management: Dependent doses analysis for anti-diabetic, antioxidant, and anti-inflammatory in STZ-induced rats

Author(s)

Keywords

Green Tea Kombucha

Diabetes Mellitus Therapy

antioxidant

anti-inflamatory

Abstract

Green Tea Kombucha (GTK), a type of fermented drink that is packed with organic acids and polyphenols, has demonstrated potent anti-diabetic, antioxidant, and anti-inflammatory properties. While GTK has exhibited potential in the management of diabetes, investigations into its optimal doses remain scarce, particularly in basic research utilizing animal models of diabetes. This study aims to assess the impact of various doses of GTK on biomarkers related to inflammation, oxidative stress, and diabetes in rats that have been made diabetic through Streptozotocin (STZ) induction. Three doses of GTK (1.25, 2.5, and 5 mL/kg BW) were administered for 14 consecutive days. The results revealed that GTK substantially reduced insulin and fasting blood glucose (FBG) concentrations, with the 2.5 mL/kg BW dose showing the most pronounced effect compared to the diabetic control rats (p-value less than 0.05). In addition, administering GTK improved oxidative stress and inflammatory biomarkers. The 5 mL/kg BW dose demonstrated the most substantial effect in reducing MDA, 4-HNE, and IL-1β in comparison to the diabetic control group, while the 2.5 mL/kg BW dose had the greatest effect in reducing IL-6. These findings indicate that GTK, particularly at 2.5 mL/kg BW, exhibits substantial anti-diabetic properties, while the 5 mL/kg BW dose demonstrates notable antioxidant and anti-inflammatory effects. This positions GTK as a promising candidate for complementary treatment in diabetes management. Further research is necessary to better understand the underlying mechanisms of GTK's effects and to determine the optimal dosage for potential clinical application.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans