Clinicopathological features of uterine sarcoma correlation

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Azmi Rizza Maulana; Tjokroprawiro Brahmana Askanda

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Journal Paper

Paper Information

Journal: Journal of Medicinal and Pharmaceutical Chemistry Research Year:2026 | Volume:8 | Issue:3 Page(s): 739-751

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Information Journal Paper

Title

Clinicopathological features of uterine sarcoma correlation

Author(s)

Azmi Rizza Maulana | Tjokroprawiro Brahmana Askanda | Issue Writer Certificate

Keywords

Endometrial stromal sarcoma

leiomyosarcoma

uterine sarcoma

Gynecology

Abstract

An uncommon and aggressive kind of uterine cancer, uterine sarcomas represent approximately 3-7% of all uterine cancers and about 1% of malignancies in the female reproductive tract. These tumors frequently have a bad prognosis and develop quickly. The prognosis of uterine sarcomas is mostly determined by histological grading. Mixed Müllerian Sarcoma (MMS), Carcinosarcomas (CS), leiomyosarcoma (LMS), Endometrial stromal sarcoma (ESS), and uncommon forms such as undifferentiated sarcoma are the five primary subtypes of uterine sarcoma according to the Gynecologic Oncology Group. The standard treatment for uterine sarcoma is surgical resection, typically involving bilateral salpingo-oophorectomy and total abdominal hysterectomy. Nevertheless, the function of adjuvant treatments like radiotherapy is still unknown, as no appreciable advantage has been seen following surgery. Because uterine sarcoma typically has a poor prognosis with high rates of metastasis and recurrence, early diagnosis and knowledge of the clinicopathological features are crucial for the best possible patient care. Further study is required to enhance survival outcomes and modify treatment procedures due to the variety of these malignancies.

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