DOSE TRIFOLIUM PRATENSE L. PROTECT AGAINST DEVELOPMENT OF FATTY STREAK IN CORONARY ARTERIES?

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ASGARI SEDIGHEH; MOSHTAGHIAN S.J.; NADERI G.A.; FATAHI Z.; HOSSEINI M.; DASHTI G.R.; ADIB SH.

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Journal: Journal of Medicinal Plants Year:2007 | Volume:6 | Issue:22 Page(s): 39-45

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Title

DOSE TRIFOLIUM PRATENSE L. PROTECT AGAINST DEVELOPMENT OF FATTY STREAK IN CORONARY ARTERIES?

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Keywords

RED CLOVERQ3

FATTY STREAKQ3

ATHEROSCLEROSISQ3

HYPERLIPIDEMICQ3

RABBITQ3

Abstract

Background: Phytoestrogens with a biological activity like estradiol are naturally found in many plants. Objective: This study was designed to investigate the effect of RED CLOVER (RC), a phytoestrogen-rich member of the legume family (Trifolium pratense L.) on the development of ATHEROSCLEROSIS in male HYPERLIPIDEMIC RABBITs. Method: Twenty RABBITs were semi-randomly distributed into four groups of five each. Two groups received either normal diet or normal diet supplemented with RC. Two other groups received similar diets to both of which 1% cholesterol was added. Results: Dietary use of RC in HYPERLIPIDEMIC RABBITs significantly decreased C-reactive protein (CRP), triglyceride (TG), total cholesterol and LDL-cholesterol (LDL-C) whereas, HDL - cholesterol (HDL-C) was significantly increased in those animals (p<0.05). FATTY STREAK formation was also significantly lower in aorta and left and right coronary arteries in the same animals due to use of dietary RC supplementation. Conclusion: These findings suggest that dietary RC may reduce cardiovascular risk factors.

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APA: Copy

ASGARI, SEDIGHEH, MOSHTAGHIAN, S.J., NADERI, G.A., FATAHI, Z., HOSSEINI, M., DASHTI, G.R., & ADIB, SH.. (2007). DOSE TRIFOLIUM PRATENSE L. PROTECT AGAINST DEVELOPMENT OF FATTY STREAK IN CORONARY ARTERIES?. JOURNAL OF MEDICINAL PLANTS, 6(22), 39-45. SID. https://sid.ir/paper/15433/en

Vancouver: Copy

ASGARI SEDIGHEH, MOSHTAGHIAN S.J., NADERI G.A., FATAHI Z., HOSSEINI M., DASHTI G.R., ADIB SH.. DOSE TRIFOLIUM PRATENSE L. PROTECT AGAINST DEVELOPMENT OF FATTY STREAK IN CORONARY ARTERIES?. JOURNAL OF MEDICINAL PLANTS[Internet]. 2007;6(22):39-45. Available from: https://sid.ir/paper/15433/en

IEEE: Copy

SEDIGHEH ASGARI, S.J. MOSHTAGHIAN, G.A. NADERI, Z. FATAHI, M. HOSSEINI, G.R. DASHTI, and SH. ADIB, “DOSE TRIFOLIUM PRATENSE L. PROTECT AGAINST DEVELOPMENT OF FATTY STREAK IN CORONARY ARTERIES?,” JOURNAL OF MEDICINAL PLANTS, vol. 6, no. 22, pp. 39–45, 2007, [Online]. Available: https://sid.ir/paper/15433/en

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