SUBACUTE TOXICITY OF ELAEAGNUS ANGUSTIFOLIA L. FRUIT SEEDS IN RATS

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KARIMI GH.; KHOIE A.; HOSSIEN REZAI H.; SHOJAIE SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Medicinal Plants Year:2003 | Volume:2 | Issue:8 Page(s): 47-54

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Title

SUBACUTE TOXICITY OF ELAEAGNUS ANGUSTIFOLIA L. FRUIT SEEDS IN RATS

Author(s)

KARIMI GH. | KHOIE A. | HOSSIEN REZAI H. | SHOJAIE SH. | Issue Writer Certificate

Keywords

ELAEAGNUS ANGUSTIFOLIAQ4

AQUEOUS EXTRACT. SUBACUTE TOXICITYQ3

ANEMIA.Q4

Abstract

The subacute toxicity of ELAEAGNUS ANGUSTIFOLIA fruit seeds extract was studied in rats. Separate groups of animals were given intraperitoneal doses of extract at 0.125, 0.25 and 0.5 g/kg daily for two weeks. Blood samples and selected organs were prepared for biochemical, hematological and histological experiments. Significant reduction of RBC, HCT and Hgb were recorded in all doses. Doses of 0.25 and 0.5 g/kg increased ALT, AST, ALP and LDH significantly and induced sever injury to liver and heart, but low effect on kidney. The results indicated that the extract was toxic for liver, heart and kidney and caused normochrome normocyte ANEMIA.

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APA: Copy

KARIMI, GH., KHOIE, A., HOSSIEN REZAI, H., & SHOJAIE, SH.. (2003). SUBACUTE TOXICITY OF ELAEAGNUS ANGUSTIFOLIA L. FRUIT SEEDS IN RATS. JOURNAL OF MEDICINAL PLANTS, 2(8), 47-54. SID. https://sid.ir/paper/15679/en

Vancouver: Copy

KARIMI GH., KHOIE A., HOSSIEN REZAI H., SHOJAIE SH.. SUBACUTE TOXICITY OF ELAEAGNUS ANGUSTIFOLIA L. FRUIT SEEDS IN RATS. JOURNAL OF MEDICINAL PLANTS[Internet]. 2003;2(8):47-54. Available from: https://sid.ir/paper/15679/en

IEEE: Copy

GH. KARIMI, A. KHOIE, H. HOSSIEN REZAI, and SH. SHOJAIE, “SUBACUTE TOXICITY OF ELAEAGNUS ANGUSTIFOLIA L. FRUIT SEEDS IN RATS,” JOURNAL OF MEDICINAL PLANTS, vol. 2, no. 8, pp. 47–54, 2003, [Online]. Available: https://sid.ir/paper/15679/en

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