CAUSES AND CLINICAL FORMS OF CUTANEOUS ADVERSE DRUG REACTIONS IN PATIENTS REFERRED TO FARSHCHIAN HOSPITAL IN HAMEDAN IN 2008 AND 2009

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FARSHCHIAN MAHMOUD; RAHMATPOUR ROKNI GHASEM; SHARIFIAN MAHNAZ

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Journal: Dermatology and Cosmetics Year:2012 | Volume:2 | Issue:4 Page(s): 215-220

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Title

CAUSES AND CLINICAL FORMS OF CUTANEOUS ADVERSE DRUG REACTIONS IN PATIENTS REFERRED TO FARSHCHIAN HOSPITAL IN HAMEDAN IN 2008 AND 2009

Author(s)

FARSHCHIAN MAHMOUD | RAHMATPOUR ROKNI GHASEM | SHARIFIAN MAHNAZ | Issue Writer Certificate

Keywords

ADVERSE DRUG REACTIONQ2

ACUTE URTICARIAQ2

EXANTEMATIC ERUPTIONQ2

FIXED DRUG ERUPTIONQ2

Abstract

Background and Aim: ADVERSE DRUG REACTIONs are inevitable outcomes of drug therapy, which may cause mortality and morbidity for those whom are treated in this way. Cutanous ADVERSE DRUG REACTIONs are abserved in 2% to 3% of inpatients but only 2% of them are considered serious and may cause death. The aim of this study was to determine the cause and clinical forms of ADVERSE DRUG REACTIONs referred to department of dermatology.Methods: This cross-sectional study that was done on patients with diagnosis of cutanous ADVERSE DRUG REACTIONs in 2007 and 2009. All patients suspected with diagnosis of ADVERSE DRUG REACTIONs were examined by an experienced dermatologist for determination of different kinds of clinical manifestations.Results: During the study period, 308 patients were recruited. Cutanous ADVERSE DRUG REACTIONs were found to be more frequent in females (63%) than in males (37%). Betalactam antibiotics were found to be the most frequent cause of adverse cutaneous drug reactions (42.7%), followed by non-steroidal anti-inflammatory drugs (16.5%). ACUTE URTICARIA was the most frequent observed drug reaction (59.2%) followed by FIXED DRUG ERUPTION (18.5%) and maculopapular rashes (14.9%).Conclusion: In this study adverse cutaneous drug reactions was mainly induced by betalactam antibiotics and non-steroidal anti-inflammatory drugs. The most common forms of cutaneous ADVERSE DRUG REACTIONs were found to be: ACUTE URTICARIA, FIXED DRUG ERUPTION and maculopapular rashes.

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APA: Copy

FARSHCHIAN, MAHMOUD, RAHMATPOUR ROKNI, GHASEM, & SHARIFIAN, MAHNAZ. (2012). CAUSES AND CLINICAL FORMS OF CUTANEOUS ADVERSE DRUG REACTIONS IN PATIENTS REFERRED TO FARSHCHIAN HOSPITAL IN HAMEDAN IN 2008 AND 2009. DERMATOLOGY AND COSMETIC, 2(4), 215-220. SID. https://sid.ir/paper/157674/en

Vancouver: Copy

FARSHCHIAN MAHMOUD, RAHMATPOUR ROKNI GHASEM, SHARIFIAN MAHNAZ. CAUSES AND CLINICAL FORMS OF CUTANEOUS ADVERSE DRUG REACTIONS IN PATIENTS REFERRED TO FARSHCHIAN HOSPITAL IN HAMEDAN IN 2008 AND 2009. DERMATOLOGY AND COSMETIC[Internet]. 2012;2(4):215-220. Available from: https://sid.ir/paper/157674/en

IEEE: Copy

MAHMOUD FARSHCHIAN, GHASEM RAHMATPOUR ROKNI, and MAHNAZ SHARIFIAN, “CAUSES AND CLINICAL FORMS OF CUTANEOUS ADVERSE DRUG REACTIONS IN PATIENTS REFERRED TO FARSHCHIAN HOSPITAL IN HAMEDAN IN 2008 AND 2009,” DERMATOLOGY AND COSMETIC, vol. 2, no. 4, pp. 215–220, 2012, [Online]. Available: https://sid.ir/paper/157674/en

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