SAFETY AND EFFICACY OF TACROLIMUS 0.03% OINTMENT IN THE TREATMENT OF ATOPIC DERMATITIS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MANSOURI PARVIN; HASOURI SOHEILA; FIROOZ ALIREZA; KHATAMI ALIREZA; ATAROD ASAL; ZARTAB HAMED; CHALANGARI REZA; MARTITS CHALANGARI KATALIN; SADEGHI FARIBORZ

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Dermatology and Cosmetics Year:2011 | Volume:2 | Issue:3 Page(s): 143-149

Download Full-Text

Persian Verion

View:

18,908

Download:

Cites:

Information Journal Paper

Title

SAFETY AND EFFICACY OF TACROLIMUS 0.03% OINTMENT IN THE TREATMENT OF ATOPIC DERMATITIS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL

Author(s)

Keywords

ATOPIC DERMATITISQ3

TREATMENTQ3

CORTICOSTEROIDQ2

CALCINEURIN INHIBITORQ2

Abstract

Background and Aim: ATOPIC DERMATITIS (AD) is a chronic, relapsing, pruritic skin disease more common in infancy and childhood. Emollients, topical CORTICOSTEROIDs, and avoidance of irritating factors are the mainstay of its TREATMENT, but fear of side effects has limited the use of topical CORTICOSTEROIDs. The objective of this study was to evaluate the safety and efficacy of topical tacrolimus 0.03% ointment in the TREATMENT of AD.Methods: In this randomized, double-blind, clinical trial, 76 patients with AD older than 2 years were randomly allocated in two groups and treated with either tacrolimus 0.03% ointment (Abu-Rayhan Co., Iran) or placebo, twice a day for 6 weeks. Responses to TREATMENT were compared every 2 weeks using SCORAD.Results: Twenty-nine patients in tacrolimus group and 26 in placebo group completed the trial. The reduction in SCORAD after 2 and 4 weeks in tacrolimus group was significantly higher than placebo group (P<0.05). The frequency of TREATMENT-induced pruritus and burning sensation was similar in both groups but erythema was more observed in the placebo group (P<0.05).Conclusion: Tacrolimus 0.03% ointment is more effective than placebo in the TREATMENT of AD.

Cites

No record.

References

No record.

Cite

APA: Copy

MANSOURI, PARVIN, HASOURI, SOHEILA, FIROOZ, ALIREZA, KHATAMI, ALIREZA, ATAROD, ASAL, ZARTAB, HAMED, CHALANGARI, REZA, MARTITS CHALANGARI, KATALIN, & SADEGHI, FARIBORZ. (2011). SAFETY AND EFFICACY OF TACROLIMUS 0.03% OINTMENT IN THE TREATMENT OF ATOPIC DERMATITIS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL. DERMATOLOGY AND COSMETIC, 2(3), 143-149. SID. https://sid.ir/paper/157727/en

Vancouver: Copy

MANSOURI PARVIN, HASOURI SOHEILA, FIROOZ ALIREZA, KHATAMI ALIREZA, ATAROD ASAL, ZARTAB HAMED, CHALANGARI REZA, MARTITS CHALANGARI KATALIN, SADEGHI FARIBORZ. SAFETY AND EFFICACY OF TACROLIMUS 0.03% OINTMENT IN THE TREATMENT OF ATOPIC DERMATITIS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL. DERMATOLOGY AND COSMETIC[Internet]. 2011;2(3):143-149. Available from: https://sid.ir/paper/157727/en

IEEE: Copy

PARVIN MANSOURI, SOHEILA HASOURI, ALIREZA FIROOZ, ALIREZA KHATAMI, ASAL ATAROD, HAMED ZARTAB, REZA CHALANGARI, KATALIN MARTITS CHALANGARI, and FARIBORZ SADEGHI, “SAFETY AND EFFICACY OF TACROLIMUS 0.03% OINTMENT IN THE TREATMENT OF ATOPIC DERMATITIS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL,” DERMATOLOGY AND COSMETIC, vol. 2, no. 3, pp. 143–149, 2011, [Online]. Available: https://sid.ir/paper/157727/en

Related Journal Papers