THE EFFECT OF ALLIUM PARADOXUM EXTRACT COMBINED WITH VOLUNTARY WHEEL RUNNING ON BRAIN AMYLOID BETA (Aβ1-42) LEVELS IN DIABETIC MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FALAH MOHAMMADI ZIA; EBRAHIMZADEH MOJTABA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sport Biosciences Year:2013 | Volume:5 | Issue:16 Page(s): 21-34

Download Full-Text

Persian Verion

View:

732

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF ALLIUM PARADOXUM EXTRACT COMBINED WITH VOLUNTARY WHEEL RUNNING ON BRAIN AMYLOID BETA (Aβ1-42) LEVELS IN DIABETIC MALE RATS

Author(s)

FALAH MOHAMMADI ZIA | EBRAHIMZADEH MOJTABA | Issue Writer Certificate

Keywords

RATSQ2

VOLUNTARY TRAININGQ2

ALLIUM PARADOXUMQ2

Aβ1-42Q1

DIABETESQ1

Abstract

Protein amyloid beta (Ab), as the pathologic hallmark of Alzheimer disease (AD), increases in the brain of diabetic patients. The aim of this study was to investigate the effect of 6 weeks of voluntary wheel running combined with ALLIUM PARADOXUM extract on cortex amyloid beta (Ab1-42) levels in diabetic RATS induced with alloxan. For this purpose, 42 male wistar RATS (weight 185+1 gr, 8 weeks old) were assigned randomly to 6 groups (n=7): normal control (c), training (T), control–diabetic (CD), diabetic–training (DT), diabetic–allium (DA), diabetic–allium–training (DAT). Subjects were DIABETES through alloxan injection (120 mg/kg dissolved in saline) intraperitoneally. Training and diabetic–training RATS inhabited in cages performed their training voluntarily on a running wheel for six weeks. At the end of the protocol, cortex Ab1-42 in T and DT groups decreased. Ab1-42 levels significantly decreased in T and DT compared with C and CD respectively (P<0.001). Also, Ab1-42 levels significantly increased in CD in comparison with C (P<0.001). Furthermore, VOLUNTARY TRAINING along with consumption of ALLIUM PARADOXUM extract decreased cortex Ab1-42 in DAT (P<0.001). VOLUNTARY TRAINING and allium extract had positive effects on decreasing Ab1-42 levels; therefore, it can be recommended as therapeutic strategy for DIABETES.

Cites

No record.

References

No record.

Cite

APA: Copy

FALAH MOHAMMADI, ZIA, & EBRAHIMZADEH, MOJTABA. (2013). THE EFFECT OF ALLIUM PARADOXUM EXTRACT COMBINED WITH VOLUNTARY WHEEL RUNNING ON BRAIN AMYLOID BETA (Aβ_1-42) LEVELS IN DIABETIC MALE RATS. SPORT BIOSCIENCES (HARAKAT), 5(16), 21-34. SID. https://sid.ir/paper/159664/en

Vancouver: Copy

FALAH MOHAMMADI ZIA, EBRAHIMZADEH MOJTABA. THE EFFECT OF ALLIUM PARADOXUM EXTRACT COMBINED WITH VOLUNTARY WHEEL RUNNING ON BRAIN AMYLOID BETA (Aβ_1-42) LEVELS IN DIABETIC MALE RATS. SPORT BIOSCIENCES (HARAKAT)[Internet]. 2013;5(16):21-34. Available from: https://sid.ir/paper/159664/en

IEEE: Copy

ZIA FALAH MOHAMMADI, and MOJTABA EBRAHIMZADEH, “THE EFFECT OF ALLIUM PARADOXUM EXTRACT COMBINED WITH VOLUNTARY WHEEL RUNNING ON BRAIN AMYLOID BETA (Aβ_1-42) LEVELS IN DIABETIC MALE RATS,” SPORT BIOSCIENCES (HARAKAT), vol. 5, no. 16, pp. 21–34, 2013, [Online]. Available: https://sid.ir/paper/159664/en

Related Journal Papers