STUDY THE EFFECT OF ECHINACEA PURPUREA EXTRACT ON CELLULAR DELAYED TYPE HYPERSENSITIVITY AND SPLENOCYTE PROLIFERATION IN BALB/C MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HASHEMI SEYED MAHMOUD; SOOUDI S.; GHAEMI AMIR; SOLEYMANJAHI H.; MOHAMMAD HASAN ZOHEYR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Cell Journal (Yakhteh) Year:2008 | Volume:9 | Issue:4 (36) Page(s): 254-261

Download Full-Text

Persian Verion

View:

1,023

Download:

Cites:

Information Journal Paper

Title

STUDY THE EFFECT OF ECHINACEA PURPUREA EXTRACT ON CELLULAR DELAYED TYPE HYPERSENSITIVITY AND SPLENOCYTE PROLIFERATION IN BALB/C MICE

Author(s)

Keywords

ECHINACEA PURPUREAQ2

SPLENOCYTE PROLIFERATIONQ3

DELAYED TYPEQ2

Abstract

Objective: Purple cone flower plant (ECHINACEA PURPUREA) is one of the mostimportant Herbal products in many countries. Up to now a lot of experiments demonstrated the controversial effects of this herb on immune system. In this research we study the in vivo and in vitro effect of Iranian E.purpurea extract on cellular immunity.Materials and Methods: At first we determined the lethal dose of E.purpurea extract after intraperitoneal injection in BALB/c mice. Then we made five groups of mice and treat them by four times intraperitoneal injection of 1 ml extract at different doses (0, 0.4, 2, 10 and 50mg/ml) during two weeks. SPLENOCYTE PROLIFERATION response to extract was assessed by MTT method. Delayed-Type Hypersensitivity (DTH) response was evaluated by priming mice with 1×108 Sheep Red Blood Cell (SRBC) injected subcutaneously in the back on day 7after treatment. Results: As a result no significant variation in weight and spleen index of test groups to control was observed. SPLENOCYTE PROLIFERATION and DTH response of test groups to control increased significantly (p<0.05).Conclusion: However these data confirmed the results of previous studies, inaddition presented the first results about significant increase in DTH response that could not be seen before. Scince the main reason of this difference refers to active compounds of herb extract, comparing effective component of this extract with that of E.purpurea cultivated in other geographical condition will consider as the next studies.

Cites

THE EFFECTS OF PLASMA TREATED ELECTROSPUN NANOFIBROUS POLY (ε-CAPROLACTONE) SCAFFOLDS WITH DIFFERENT ORIENTATIONS ON MOUSE EMBRYONIC STEM CELL PROLIFERATION

References

No record.

Cite

APA: Copy

HASHEMI, SEYED MAHMOUD, SOOUDI, S., MOHAMMAD HASAN, ZOHEYR, GHAEMI, AMIR, & SOLEYMANJAHI, H.. (2008). STUDY THE EFFECT OF ECHINACEA PURPUREA EXTRACT ON CELLULAR DELAYED TYPE HYPERSENSITIVITY AND SPLENOCYTE PROLIFERATION IN BALB/C MICE. CELL JOURNAL (YAKHTEH), 9(4 (36)), 254-261. SID. https://sid.ir/paper/16477/en

Vancouver: Copy

HASHEMI SEYED MAHMOUD, SOOUDI S., MOHAMMAD HASAN ZOHEYR, GHAEMI AMIR, SOLEYMANJAHI H.. STUDY THE EFFECT OF ECHINACEA PURPUREA EXTRACT ON CELLULAR DELAYED TYPE HYPERSENSITIVITY AND SPLENOCYTE PROLIFERATION IN BALB/C MICE. CELL JOURNAL (YAKHTEH)[Internet]. 2008;9(4 (36)):254-261. Available from: https://sid.ir/paper/16477/en

IEEE: Copy

SEYED MAHMOUD HASHEMI, S. SOOUDI, ZOHEYR MOHAMMAD HASAN, AMIR GHAEMI, and H. SOLEYMANJAHI, “STUDY THE EFFECT OF ECHINACEA PURPUREA EXTRACT ON CELLULAR DELAYED TYPE HYPERSENSITIVITY AND SPLENOCYTE PROLIFERATION IN BALB/C MICE,” CELL JOURNAL (YAKHTEH), vol. 9, no. 4 (36), pp. 254–261, 2008, [Online]. Available: https://sid.ir/paper/16477/en

Related Journal Papers