THE EFFECT OF FLUOXETIN AND CLOMIPRAMIN ON BLOOD SUGAR, CHOLESTEROL, AND WEIGHT OF OBSESSIVE - COMPULSIV CHILDREN AND ADOLESCENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOHAMMADI M.R.; MOUMENI F.; TORKZABAN R.; GHAELI P.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Psychiatry and Clinical Psychology Year:2003 | Volume:8 | Issue:3 (31) Page(s): 12-19

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

28,190

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF FLUOXETIN AND CLOMIPRAMIN ON BLOOD SUGAR, CHOLESTEROL, AND WEIGHT OF OBSESSIVE - COMPULSIV CHILDREN AND ADOLESCENTS

Author(s)

MOHAMMADI M.R. | MOUMENI F. | TORKZABAN R. | GHAELI P. | Issue Writer Certificate

Keywords

FLOUXETINEQ4

CLOMIPRAMINEQ4

BLOOD SUGARQ4

TRIGLYCERIDEQ4

CHOLESTEROLQ3

LIVER FUNCTION TESTQ4

OBSESSIVE-COMPULSIVE DISORDERQ3

Abstract

Objectives: Evaluating the effects of fluoxetine and CLOMIPRAMINE on fasting BLOOD SUGAR, tri-glyceride, CHOLESTEROL, weight, and liver function of obsessive-compulsive of Iranian children and adolescents. Method: 30 patients (7-17 yrs.) referred by Roozbeh Hospital with the diag-nosis of OBSESSIVE-COMPULSIVE DISORDER (OCD), were selected as the subjects. Clinical inte-rviews based on DSM-IV, Yale-Brown Obsessive-Compulsive Scale (YBOS) and Maudseley Obsessive Compulsive Inventory (MOCI) was used for the purpose of diagnosis. The sub-jects were randomly assigned to two groups; each composed of 15 subjects. For a period of 8 weeks, in a double blind clinical trial, one group received fluoxetine and the other group received CLOMIPRAMINE. The first group started with 10 to 20 mg. of fluoxetine; the dosage was ultimately increased to 20-60 mg. per day in the second week. The second group received 25 mg. of CLOMIPRAMINE in the beginning and then in the second week, it was raised up to 75-200 mg. per day. The severity of OCD was measured by YBOS and MOCI at the beginning and end of the study. TRIGLYCERIDE, CHOLESTEROL, fasting BLOOD SUGAR, and weight were first measured at the initial phase, and then two, four, and 8 weeks after the initiation of the medi-cation. The results were analyzed by descriptive statistics and t-test. Finding: This study showed that fluoxetine decreased fasting BLOOD SUGAR, CHOLESTEROL, and TRIGLYCERIDE signi-ficantly; fluoxetine increased the density of ALP of liver function. On the other hand, clomi-pramine decreased fasting BLOOD SUGAR, CHOLESTEROL, and TRIGLYCERIDE; but had no effect on ALP of liver function. Both fluoxetine and CLOMIPRAMINE caused an increase in the density of SGPT and SGOT of liver function. Whereas after eight weeks of treatment, fluoxetine had little impact on the subjects’ weight, CLOMIPRAMINE significantly increased their weight. Results: fluoxetine is preferred in treatment of OCD patients who have over-weight issue and also suffer from cardiovascular or diabetic disorders.

Cites

References

No record.

Cite

APA: Copy

MOHAMMADI, M.R., MOUMENI, F., TORKZABAN, R., & GHAELI, P.. (2003). THE EFFECT OF FLUOXETIN AND CLOMIPRAMIN ON BLOOD SUGAR, CHOLESTEROL, AND WEIGHT OF OBSESSIVE - COMPULSIV CHILDREN AND ADOLESCENTS . IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, 8(3 (31)), 12-19. SID. https://sid.ir/paper/17087/en

Vancouver: Copy

MOHAMMADI M.R., MOUMENI F., TORKZABAN R., GHAELI P.. THE EFFECT OF FLUOXETIN AND CLOMIPRAMIN ON BLOOD SUGAR, CHOLESTEROL, AND WEIGHT OF OBSESSIVE - COMPULSIV CHILDREN AND ADOLESCENTS . IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY[Internet]. 2003;8(3 (31)):12-19. Available from: https://sid.ir/paper/17087/en

IEEE: Copy

M.R. MOHAMMADI, F. MOUMENI, R. TORKZABAN, and P. GHAELI, “THE EFFECT OF FLUOXETIN AND CLOMIPRAMIN ON BLOOD SUGAR, CHOLESTEROL, AND WEIGHT OF OBSESSIVE - COMPULSIV CHILDREN AND ADOLESCENTS ,” IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, vol. 8, no. 3 (31), pp. 12–19, 2003, [Online]. Available: https://sid.ir/paper/17087/en

Related Journal Papers