THE ELECTROPHORETICAL PATTERN OF PREMATURE PLACENTAL COLLAGENS

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POURKABIR R.; MALEKNIA N.; PASALAR P.

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Paper Information

Journal: Avicenna Journal of Clinical Medicine Year:2002 | Volume:9 | Issue:1 (SN 23) Page(s): 27-31

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Information Journal Paper

Title

THE ELECTROPHORETICAL PATTERN OF PREMATURE PLACENTAL COLLAGENS

Author(s)

POURKABIR R. | MALEKNIA N. | PASALAR P. | Issue Writer Certificate

Keywords

COLLAGENQ4

ELECTROPHORESISQ4

PLACENTAQ4

Abstract

Serveral different types of COLLAGEN have been identified invivo. Human PLACENTA has been employed by a number of investigators over the past decade as a starting material for isolation and characterization of different genetic types of COLLAGEN including type I, III, IV and IV molecules. Proteases of the PLACENTA participate in the degradation of intracellular and extracelluar matrix proteins. To extract COLLAGEN types IV and I+III, a healthy PLACENTA at term (38 weeks) and a premature PLACENTA (14 weeks) were placed under pepsin digestion using minimum quantity. The steps of extraction were controlled by the SDS-PAGE. The electrophoretical patterns of premature PLACENTAl COLLAGEN indicated that the number of COLLAGEN chains types IV and I+III in premature PLACENTA were less than that of the healthy PLACENTA at term. According to electrophoretical pattern in the premature PLACENTA , there were not 2 (IV) , 11 (I) , 12 (I) and 1 (III) chains. Thus, it is probable that in some of the repeating abortion the synthesis of COLLAGEN is decreased or degradation of COLLAGEN is increased. So it is suggested to measure the serum and cervix COLLAGENase in women who had unexplained abortions.

Cites

A STUDY OF THE KINDS OF PLACENTAL COLLEGENS FROM IRANIAN WOMEN TO DETERMINE THE STANDARD RATE OF PLACENTAL COLLAGEN

References

استخراج و تخلیص کلاژن نوع IV از جفت انسان

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APA: Copy

POURKABIR, R., MALEKNIA, N., & PASALAR, P.. (2002). THE ELECTROPHORETICAL PATTERN OF PREMATURE PLACENTAL COLLAGENS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 9(1 (SN 23)), 27-31. SID. https://sid.ir/paper/17344/en

Vancouver: Copy

POURKABIR R., MALEKNIA N., PASALAR P.. THE ELECTROPHORETICAL PATTERN OF PREMATURE PLACENTAL COLLAGENS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2002;9(1 (SN 23)):27-31. Available from: https://sid.ir/paper/17344/en

IEEE: Copy

R. POURKABIR, N. MALEKNIA, and P. PASALAR, “THE ELECTROPHORETICAL PATTERN OF PREMATURE PLACENTAL COLLAGENS,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 9, no. 1 (SN 23), pp. 27–31, 2002, [Online]. Available: https://sid.ir/paper/17344/en

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