EFFECT OF ACARBOSE ON CONTROL OF METABOLIC PARAMETERS IN PATIENTS WITH DIABETES TYPE 1

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZIAEE A.; HASHEMIPOOR S.; KARIMZADEH T.; SHAHNAZARI S.; JAVADI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Clinical Medicine Year:2012 | Volume:19 | Issue:2 (SN 64) Page(s): 5-10

Download Full-Text

Persian Verion

View:

1,206

Download:

Cites:

Information Journal Paper

Title

EFFECT OF ACARBOSE ON CONTROL OF METABOLIC PARAMETERS IN PATIENTS WITH DIABETES TYPE 1

Author(s)

Keywords

ACARBOSEQ2

METABOLIC CONTROLQ2

DIABETES MELLITUSQ2

TYPE 1Q2

Abstract

Introduction & Objective: ACARBOSE is an intestinal alpha-glucosidase inhibitor that delays absorption of carbohydrates. Findings of some studies show that it has been effective in better control of blood glucose in patients with diabetes TYPE 1. The goal of this study is to investigate the effect of administration of ACARBOSE on glycemic & lipid parameters and daily insulin requirements and tolerability in TYPE 1 diabetic patient.Materials & Methods: This was a clinical trial randomized double blind placebo controlled study. Performed on patients with history of at least 1 year diabetes TYPE 1 and had HbA1c³7.5%. Patients with Cr³2, partial GI obstruction or IBD were excluded from the study. 45 patients were randomized to be administered ACARBOSE or placebo for 12 weeks. Initial dose of ACARBOSE was 25 mg T.D.S for 2 weeks, and then it was increased to 50 mg T.D.S for 10 weeks. BMI, FBS, 2hpp, HbA1c, Total cholesterol, HDL, LDL, TG and Insulin dosage were investigated monthly.Results: The values of BMI, FBS, 2hpp, HbA1c, Total cholesterol, and TG & Insulin requirements decreased significantly in the case group compared to the controls (P=0.003, P=0.005, P<0.001, P=0.001, P=0.003, P<0.001, P<0.001, respectively); but no significant changes were observed in HDL & LDL levels.Conclusion: Administration of ACARBOSE together with insulin to TYPE 1 diabetic patient can be valuable in improving METABOLIC CONTROL (BMI, FBS, 2hpp, HbA1c, Total cholesterol and TG).

Cites

No record.

References

No record.

Cite

APA: Copy

ZIAEE, A., HASHEMIPOOR, S., KARIMZADEH, T., SHAHNAZARI, S., & JAVADI, A.. (2012). EFFECT OF ACARBOSE ON CONTROL OF METABOLIC PARAMETERS IN PATIENTS WITH DIABETES TYPE 1. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 19(2 (SN 64)), 5-10. SID. https://sid.ir/paper/17605/en

Vancouver: Copy

ZIAEE A., HASHEMIPOOR S., KARIMZADEH T., SHAHNAZARI S., JAVADI A.. EFFECT OF ACARBOSE ON CONTROL OF METABOLIC PARAMETERS IN PATIENTS WITH DIABETES TYPE 1. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2012;19(2 (SN 64)):5-10. Available from: https://sid.ir/paper/17605/en

IEEE: Copy

A. ZIAEE, S. HASHEMIPOOR, T. KARIMZADEH, S. SHAHNAZARI, and A. JAVADI, “EFFECT OF ACARBOSE ON CONTROL OF METABOLIC PARAMETERS IN PATIENTS WITH DIABETES TYPE 1,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 19, no. 2 (SN 64), pp. 5–10, 2012, [Online]. Available: https://sid.ir/paper/17605/en

Related Journal Papers