THE EFFECTS OF DIAZINON ON THE DEVELOPMENT OF BALB/C MICE EMBRYOS IN 3TH TO 6TH DAYS OF PREGNANCY

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RASTGAR GHARAHSHIRAN S.; TORABZADEH P.; SAFFARI S.

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Journal: JOURNAL OF ANIMAL BIOLOGY Year:2017 | Volume:9 | Issue:2 Page(s): 27-36

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Title

THE EFFECTS OF DIAZINON ON THE DEVELOPMENT OF BALB/C MICE EMBRYOS IN 3TH TO 6TH DAYS OF PREGNANCY

Author(s)

RASTGAR GHARAHSHIRAN S. | TORABZADEH P. | SAFFARI S. | Issue Writer Certificate

Keywords

AGRICULTURAL PESTICIDESQ1

DIAZINONQ2

EMBRYO WEIGHTQ1

PLACENTAL WEIGHTQ2

MOUSE EMBRYOQ2

Abstract

Diazinon is one of AGRICULTURAL PESTICIDES and organophosphate pesticide, because the chemical structure and the effects have been devastating on nervous, respiratory and digestive systems in recent years there have been studied. But it is effects on the embryo especially during pregnancy have not been reviewed. Therefore in study The Biological effects of pesticide DIAZINON on the development of Balb/C MOUSE EMBRYOs Third to Sixth Days of pregnancy. In this study 90 female Balb/C mice were randomly divided into 6 equal groups acontrol group (non- injection) and sham (injection of saline) and 4 experimental groups. The lethal dose LD50 was determined in condition of 11.09 ml/kg.bw in vivo and selected dose for injection 0.4 ml/kg.bw. Injection was done on MOUSE EMBRYOs 3Th to 6Th days of pregnancy by enema. Then the mouse were sacrificed on day 15 of pregnancy.For security of results above experiences was repeated three times. Data was checked with SPSS17 software and Duncan test subjest to (P<0.05) and (P<0.001). After a comparative study at this dose, has been observed a significant decrease in the EMBRYO WEIGHT and PLACENTAL WEIGHT and Crown – Rump Length (CR), were compared with control and witness groups. According to the findings, nnegative effects of DIAZINON use as pesticides in agricultural products, On the MOUSE EMBRYOs and It is recommended to protect the environment and human health, especially pregnant women Use of non-chemical methods to control pests.

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APA: Copy

RASTGAR GHARAHSHIRAN, S., TORABZADEH, P., & SAFFARI, S.. (2017). THE EFFECTS OF DIAZINON ON THE DEVELOPMENT OF BALB/C MICE EMBRYOS IN 3^TH TO 6^TH DAYS OF PREGNANCY. JOURNAL OF ANIMAL BIOLOGY, 9(2), 27-36. SID. https://sid.ir/paper/176867/en

Vancouver: Copy

RASTGAR GHARAHSHIRAN S., TORABZADEH P., SAFFARI S.. THE EFFECTS OF DIAZINON ON THE DEVELOPMENT OF BALB/C MICE EMBRYOS IN 3^TH TO 6^TH DAYS OF PREGNANCY. JOURNAL OF ANIMAL BIOLOGY[Internet]. 2017;9(2):27-36. Available from: https://sid.ir/paper/176867/en

IEEE: Copy

S. RASTGAR GHARAHSHIRAN, P. TORABZADEH, and S. SAFFARI, “THE EFFECTS OF DIAZINON ON THE DEVELOPMENT OF BALB/C MICE EMBRYOS IN 3^TH TO 6^TH DAYS OF PREGNANCY,” JOURNAL OF ANIMAL BIOLOGY, vol. 9, no. 2, pp. 27–36, 2017, [Online]. Available: https://sid.ir/paper/176867/en

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