THE BIOLOGICAL EFFECTS OF AQUEOUS EXTRACT OFEPHEDRA MAJOR ON THE DEVELOPMENT OF BALB/C MOUSE EMBRYOS 7TH TO 10TH DAYS OF PREGNANCY

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SAFFARI S.; TORABZADEH P.; MOUSAVI DOHOOII S.M.

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Journal: JOURNAL OF ANIMAL BIOLOGY Year:2016 | Volume:9 | Issue:1 Page(s): 19-27

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Title

THE BIOLOGICAL EFFECTS OF AQUEOUS EXTRACT OFEPHEDRA MAJOR ON THE DEVELOPMENT OF BALB/C MOUSE EMBRYOS 7TH TO 10TH DAYS OF PREGNANCY

Author(s)

SAFFARI S. | TORABZADEH P. | MOUSAVI DOHOOII S.M. | Issue Writer Certificate

Keywords

EPHEDRA MAJORQ1

EMBRYO WEIGHTQ1

PLACENTAL WEIGHTQ2

MOUSE EMBRYOQ2

Abstract

Aqueous extract ofEPHEDRA MAJOR used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on the body especially during pregnancy have not been reviewed. Therefore in study The Biological effects of aqueous extract ofEPHEDRA MAJOR on the development Balb.C MOUSE EMBRYOs 7Th to 10Th days of pregnancy. In this study 50 female Balb.C mice were randomly divided into 6 groups including: control group (non- injection), sham group (injection of saline) and 4 experimental groups. Lethal dose of LD50 was determined in condition of 3086 mg.kg.bw in vivo and selected dose for injection 300 mg.kg.bw. Injection was done on the seventh to tenth days by enema. Then the mouse were sacrificed on day 15 of pregnancy.For security of results above experiences was repeated three times. Data was checked with SPSS21 software and Duncan test subjest to (P<0.001). After a comparative study at this dose, a significant decrease (P<0.001) in the Crown– Rump Length (CR), EMBRYO WEIGHT and PLACENTAL WEIGHT were compared with control and witess groups. In according to this observations can be concluded aqueous extract ofEPHEDRA MAJOR is caused to abort and tratogenic and using this herb is dangerous during pregnancy and may be use as a contraceptive pill in future.

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APA: Copy

SAFFARI, S., TORABZADEH, P., & MOUSAVI DOHOOII, S.M.. (2016). THE BIOLOGICAL EFFECTS OF AQUEOUS EXTRACT OFEPHEDRA MAJOR ON THE DEVELOPMENT OF BALB/C MOUSE EMBRYOS 7^TH TO 10^TH DAYS OF PREGNANCY. JOURNAL OF ANIMAL BIOLOGY, 9(1), 19-27. SID. https://sid.ir/paper/176663/en

Vancouver: Copy

SAFFARI S., TORABZADEH P., MOUSAVI DOHOOII S.M.. THE BIOLOGICAL EFFECTS OF AQUEOUS EXTRACT OFEPHEDRA MAJOR ON THE DEVELOPMENT OF BALB/C MOUSE EMBRYOS 7^TH TO 10^TH DAYS OF PREGNANCY. JOURNAL OF ANIMAL BIOLOGY[Internet]. 2016;9(1):19-27. Available from: https://sid.ir/paper/176663/en

IEEE: Copy

S. SAFFARI, P. TORABZADEH, and S.M. MOUSAVI DOHOOII, “THE BIOLOGICAL EFFECTS OF AQUEOUS EXTRACT OFEPHEDRA MAJOR ON THE DEVELOPMENT OF BALB/C MOUSE EMBRYOS 7^TH TO 10^TH DAYS OF PREGNANCY,” JOURNAL OF ANIMAL BIOLOGY, vol. 9, no. 1, pp. 19–27, 2016, [Online]. Available: https://sid.ir/paper/176663/en

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