CYTOTOXICITY EFFECTS OF BISHOP'S FLOWER (AMMI MAJUS) EXTRACT ON THE CANCER CELL LINES HELA AND MCF-7

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NEMATI F.; ESLAMI JADIDI B.; TALEBI DARABI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ANIMAL BIOLOGY Year:2013 | Volume:5 | Issue:3 Page(s): 59-66

Download Full-Text

Persian Verion

View:

1,628

Download:

Cites:

Information Journal Paper

Title

CYTOTOXICITY EFFECTS OF BISHOP'S FLOWER (AMMI MAJUS) EXTRACT ON THE CANCER CELL LINES HELA AND MCF-7

Author(s)

NEMATI F. | ESLAMI JADIDI B. | TALEBI DARABI M. | Issue Writer Certificate

Keywords

CYTOTOXICITYQ1

ETANOLIC EXTRACTIONQ2

AMMI MAJUSQ2

HELA CELL LINEQ2

MCF7 CELL LINEQ2

Abstract

Today many of the treatment methods are used to treat cancer. Unfortunately, in most cases very poor response is often associated with undesirable side effects. Lack of response to treatment and the rapid growth of the disease, has been made researchers to achieve more effective drugs with fewer side effects. In this study the effect of ethanolic extraction of the Bishop's Flower, AMMI MAJUS on the cancer cell lines Hela and MCF-7 were examined. Cells were cultured in cell culture flasks then transferred to 96 well plates with 10,000 cells. Cells were exposed to different concentrations of AMMI MAJUS. The CYTOTOXICITY of AMMI MAJUS was assessed using the MTT assay after 72 hours. The results of this study showed that ethanolic extract of AMMI MAJUS on Hela cells was significantly reduced the cells grow compared with controls after 72 h. The calculated IC50, was 1.922 mg / ml. The CYTOTOXICITY effect this extract on MCF7 showed that AMMI MAJUS was significantly reduced the MCF7 cells grow compared with controls after 72 h. The calculated IC50, was 10 mg / ml. The effect of this extracts on normal cells (lymphocytes and monocytes in blood) is granted, the results show that the concentration of 10 mg / ml extracts had no effect on normal cells. The results suggest that ethanolic extract of the plant AMMI MAJUS inhibits growth of cancer cells MCF7 and Hela.

Cites

No record.

References

Cite

APA: Copy

NEMATI, F., ESLAMI JADIDI, B., & TALEBI DARABI, M.. (2013). CYTOTOXICITY EFFECTS OF BISHOP'S FLOWER (AMMI MAJUS) EXTRACT ON THE CANCER CELL LINES HELA AND MCF-7. JOURNAL OF ANIMAL BIOLOGY, 5(3), 59-66. SID. https://sid.ir/paper/176962/en

Vancouver: Copy

NEMATI F., ESLAMI JADIDI B., TALEBI DARABI M.. CYTOTOXICITY EFFECTS OF BISHOP'S FLOWER (AMMI MAJUS) EXTRACT ON THE CANCER CELL LINES HELA AND MCF-7. JOURNAL OF ANIMAL BIOLOGY[Internet]. 2013;5(3):59-66. Available from: https://sid.ir/paper/176962/en

IEEE: Copy

F. NEMATI, B. ESLAMI JADIDI, and M. TALEBI DARABI, “CYTOTOXICITY EFFECTS OF BISHOP'S FLOWER (AMMI MAJUS) EXTRACT ON THE CANCER CELL LINES HELA AND MCF-7,” JOURNAL OF ANIMAL BIOLOGY, vol. 5, no. 3, pp. 59–66, 2013, [Online]. Available: https://sid.ir/paper/176962/en

Related Journal Papers