IS OVARIAN MASS MALIGNANCY PREDICTION ACCURACY INCREASED BY ADDING SERUM CA125 MEASUREMENT TO SONOGRAPHIC FINDINGS?

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ARAB M.; MAKTABI M.; ZHAM H.; KIMIAEI P.; DAVALO SH.

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Journal: Avicenna Journal of Clinical Medicine Year:2012 | Volume:18 | Issue:4 (SN 62) Page(s): 37-40

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Title

IS OVARIAN MASS MALIGNANCY PREDICTION ACCURACY INCREASED BY ADDING SERUM CA125 MEASUREMENT TO SONOGRAPHIC FINDINGS?

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Keywords

CA-125 ANTIGENQ2

OVARIAN NEOPLASMSQ2

ULTRASONOGRAPHYQ3

Abstract

Introduction & Objective: The aim of the present study is to determine the accuracy of malignancy prediction in adnexal mass if CA125 measurement is added to sonographic findings.Materials & Methods: In a cross sectional study, AUC of ROC Curve of malignancy prediction based on sonographic findings in comparison to a new model (OMPS2) based on sonography plus serum CA125 was calculated. Pathologic reports of 430 operated adnexal masses were included in the study. Logistic regression analysis was used.Results: New model (OMPS2) was constructed as follow: OMPS1+1.444 (if CA125=36-200) or 3.842 (if CA125 is above 200).AUC of ROC curve of malignancy prediction increased from 78.1% (based on OMPS1) to 84.3% (in OMPS2).Conclusion: Serum CA125 measurement in addition to sonography increased the accuracy of malignancy prediction in comparison to only sonography.

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APA: Copy

ARAB, M., MAKTABI, M., ZHAM, H., KIMIAEI, P., & DAVALO, SH.. (2012). IS OVARIAN MASS MALIGNANCY PREDICTION ACCURACY INCREASED BY ADDING SERUM CA125 MEASUREMENT TO SONOGRAPHIC FINDINGS?. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 18(4 (SN 62)), 37-40. SID. https://sid.ir/paper/17736/en

Vancouver: Copy

ARAB M., MAKTABI M., ZHAM H., KIMIAEI P., DAVALO SH.. IS OVARIAN MASS MALIGNANCY PREDICTION ACCURACY INCREASED BY ADDING SERUM CA125 MEASUREMENT TO SONOGRAPHIC FINDINGS?. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2012;18(4 (SN 62)):37-40. Available from: https://sid.ir/paper/17736/en

IEEE: Copy

M. ARAB, M. MAKTABI, H. ZHAM, P. KIMIAEI, and SH. DAVALO, “IS OVARIAN MASS MALIGNANCY PREDICTION ACCURACY INCREASED BY ADDING SERUM CA125 MEASUREMENT TO SONOGRAPHIC FINDINGS?,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 18, no. 4 (SN 62), pp. 37–40, 2012, [Online]. Available: https://sid.ir/paper/17736/en

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