SOY, SOY ISOFLAVONES AND BREAST CANCER RISK

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KIMIAGAR MASUD; HEJAZI EHSAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Researcher Bulletin of Medical Sciences Year:2011 | Volume:16 | Issue:2 (80) Page(s): 52-58

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Information Journal Paper

Title

SOY, SOY ISOFLAVONES AND BREAST CANCER RISK

Author(s)

KIMIAGAR MASUD | HEJAZI EHSAN | Issue Writer Certificate

Keywords

SOY FOODSQ3

SOY ISOFLAVONESQ2

ESTROGEN REPLACEMENT THERAPYQ3

BREAST NEOPLASMSQ2

Abstract

In recent years there has been considerable investigation about the potentials of soyfoods to reduce the risk of cancer, particularly breast cancer. Isoflavones are compounds with a chemical structure similar to estrogen and can bind to estrogen receptor. The relationship between soyfoods and breast cancer has become a controversial issue because of concerns -based mostly on some in vitro and rodent data- that isoflavones may stimulate the growth of existing estrogen-sensitive breast tumors. However, some have indicated that SOY ISOFLAVONES have antitumor and antiproliferative effects. The epidemiologic data are generally consistent with the animal studies, showing no increased risk. In limited clinical studies there is no evidence that isoflavone intake increases tumor growth or proliferation of carcinoma cells. Also, epidemiological studies on breast cancer survival showed that SOY ISOFLAVONES decrease recurrence and mortality of disease. Furthermore, it is demonstrated that in healthy women the pharmacologic dose of estrogen has very low if any risk for breast cancer. Because of the increasing popularity of soyfoods and the commercial availability of isoflavone supplements and existing concern regarding the estrogen-like effects of isoflavones in the breast, more clinical research seems to be necessary.

Cites

EFFECTS OF COMBINED SOY ISOFLAVONE EXTRACT AND DOCETAXEL TREATMENT ON MURINE 4T1 BREAST TUMOR MODEL

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APA: Copy

KIMIAGAR, MASUD, & HEJAZI, EHSAN. (2011). SOY, SOY ISOFLAVONES AND BREAST CANCER RISK. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 16(2 (80)), 52-58. SID. https://sid.ir/paper/18249/en

Vancouver: Copy

KIMIAGAR MASUD, HEJAZI EHSAN. SOY, SOY ISOFLAVONES AND BREAST CANCER RISK. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2011;16(2 (80)):52-58. Available from: https://sid.ir/paper/18249/en

IEEE: Copy

MASUD KIMIAGAR, and EHSAN HEJAZI, “SOY, SOY ISOFLAVONES AND BREAST CANCER RISK,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 16, no. 2 (80), pp. 52–58, 2011, [Online]. Available: https://sid.ir/paper/18249/en

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