A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches

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SHIRZAIY MASOOMEH; HEIDARI FATHEMEH

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Journal: JOURNAL OF RESEARCH IN DENTAL SCIENCES Year:2020 | Volume:17 | Issue:1(63) Page(s): 64-72

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Title

A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches

Author(s)

SHIRZAIY MASOOMEH | HEIDARI FATHEMEH | Issue Writer Certificate

Keywords

Areca nutQ1

oral submucous fibrosisQ1

oral cancerQ3

Abstract

Background and AIM: oral submucous fibrosis (OSF) is an oral premalignant condition with highest premalignant potential among oral precancerous lesions which characterized with inflammation and progressive fibrosis of submucosal oral tissues (cause to significant irreversible rigidity and trismus). During the years, many classification systems have been proposed in medicine literatures on basis clinical, functional and histopathological aspects. This review study was done with aim of assessment and presentation of proper classification systems to the physicians use in therapeutic centers for early diagnosis, disease progression and proper treatment plan for OSF patients. Material & methods: Research was done in pubmed, Google scholar, science direct, web of sciences and Scopus databases and totally, 30 articles were selected. Results: The study resulted in a new and appropriate classification system covering all aspects of the disease including clinical, functional, histological, treatment and prognosis. Also pathogenesis and new management of OSF have been discussed. Conclusion: Attempts to provide and update the knowledge of Submucous fibrosis classification system to assist clinicians, can be useful in researches and classifying this potentially malignant disease and help greatly in the early diagnosis, proper management and reduction of morbidity and mortality of the disease.

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APA: Copy

SHIRZAIY, MASOOMEH, & HEIDARI, FATHEMEH. (2020). A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches. JOURNAL OF RESEARCH IN DENTAL SCIENCES, 17(1(63) ), 64-72. SID. https://sid.ir/paper/184608/en

Vancouver: Copy

SHIRZAIY MASOOMEH, HEIDARI FATHEMEH. A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches. JOURNAL OF RESEARCH IN DENTAL SCIENCES[Internet]. 2020;17(1(63) ):64-72. Available from: https://sid.ir/paper/184608/en

IEEE: Copy

MASOOMEH SHIRZAIY, and FATHEMEH HEIDARI, “A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches,” JOURNAL OF RESEARCH IN DENTAL SCIENCES, vol. 17, no. 1(63) , pp. 64–72, 2020, [Online]. Available: https://sid.ir/paper/184608/en

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