DESIGNING AND FABRICATION OF BIODEGRADABLE COMPOSITE MEMBRANES BASED ON CHITOSAN FIBROBINPOLYVINYLALCOHOL BY SOLVENT CASTING METHOD FOR BONE TISSUE ENGINEERING

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JABARI FARZANEH; HOUSHMAND BEHZAD; HESARAKI SAEED

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Journal: JOURNAL OF RESEARCH IN DENTAL SCIENCES Year:2019 | Volume:15 | Issue:4 (58) Page(s): 201-210

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Title

DESIGNING AND FABRICATION OF BIODEGRADABLE COMPOSITE MEMBRANES BASED ON CHITOSAN FIBROBINPOLYVINYLALCOHOL BY SOLVENT CASTING METHOD FOR BONE TISSUE ENGINEERING

Author(s)

JABARI FARZANEH | HOUSHMAND BEHZAD | HESARAKI SAEED | Issue Writer Certificate

Keywords

BIODEGRADABLE MEMBRANEQ1

FIBROINQ1

BONE REGENERATIONQ2

Abstract

Background & Aim: Designing and fabrication of biodegradable and bioactive membranes are the importantissues in guided BONE REGENERATION while these membranes should maintain their structural integrity duringrepair, have the required mechanical, physical and biological properties and selective permeability. One of theapproaches to achieve this purpose is the fabrication of composite membranes based on biopolymers. Materials and Methods: In this experimental research, the fabrication and characterization of compositemembranes composed of chitosan-silk fibrobin and polyvinyl alcohol have been performed. chitosan solution andfibroin-polyvinyl alcohol solution were mixed in different ratio and membranes were fabricated by solventcasting method. Mechanical properties such as tensile strength and ultimate strain percentage and physicalproperties including water absorption and degradation rate of membranes were investigated. Results: The FTIR spectrum of the extracted fibrobin showed peaks at 1650 cm-1, 1530 cm-1, and 1244 cm-1. The XRD and SEM images showed that the synthesized fibrin has the structure of beta plates. The results ofphysical and mechanical properties of membranes showed that the presence of FIBROIN in the compositionincreases the mechanical strength. Increasing the amount of chitosan in the composition increased the waterabsorption and degradation rate of membranes. Conclusion: FIBROIN is a suitable polymer for increasing mechanical strength, controlling the degradation rate, improving the water absorption ability and is so biocompatible. Solvent casting method with controlling theviscosity of solution and solvent evaporation rate is appropriate method for fabrication the membranes.

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APA: Copy

JABARI, FARZANEH, HOUSHMAND, BEHZAD, & HESARAKI, SAEED. (2019). DESIGNING AND FABRICATION OF BIODEGRADABLE COMPOSITE MEMBRANES BASED ON CHITOSAN FIBROBINPOLYVINYLALCOHOL BY SOLVENT CASTING METHOD FOR BONE TISSUE ENGINEERING. JOURNAL OF RESEARCH IN DENTAL SCIENCES, 15(4 (58) ), 201-210. SID. https://sid.ir/paper/184675/en

Vancouver: Copy

JABARI FARZANEH, HOUSHMAND BEHZAD, HESARAKI SAEED. DESIGNING AND FABRICATION OF BIODEGRADABLE COMPOSITE MEMBRANES BASED ON CHITOSAN FIBROBINPOLYVINYLALCOHOL BY SOLVENT CASTING METHOD FOR BONE TISSUE ENGINEERING. JOURNAL OF RESEARCH IN DENTAL SCIENCES[Internet]. 2019;15(4 (58) ):201-210. Available from: https://sid.ir/paper/184675/en

IEEE: Copy

FARZANEH JABARI, BEHZAD HOUSHMAND, and SAEED HESARAKI, “DESIGNING AND FABRICATION OF BIODEGRADABLE COMPOSITE MEMBRANES BASED ON CHITOSAN FIBROBINPOLYVINYLALCOHOL BY SOLVENT CASTING METHOD FOR BONE TISSUE ENGINEERING,” JOURNAL OF RESEARCH IN DENTAL SCIENCES, vol. 15, no. 4 (58) , pp. 201–210, 2019, [Online]. Available: https://sid.ir/paper/184675/en

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