Antioxidant Effects of Swimming Training and Curcumin in Withdrawal Period of Alcohol Overdose in Rats

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Seyed A.; Farsi Sirous; HOSSEINI S.A.; KAKA GH.

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Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2018 | Volume:8 | Issue:3 Page(s): 901-910

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Title

Antioxidant Effects of Swimming Training and Curcumin in Withdrawal Period of Alcohol Overdose in Rats

Author(s)

Seyed A. | Farsi Sirous | HOSSEINI S.A. | KAKA GH. | Issue Writer Certificate

Keywords

Swimming trainingQ1

CurcuminQ1

AntioxidantQ3

AlcoholQ2

Abstract

Background & Objective: Alcohol overdose can induce increment in free radicals. The present study aimed to investigate the effect of Swimming training and Curcumin in withdrawal period of Alcohol overdose on superoxide dismutase (SOD), glutathione peroxidase (GPX), total Antioxidant capacity (TAC), malone dealdeid (MDA) and protein carbonyl (PC) of rats. Materials & Methods: 40 rats were selected and administered Alcohol every 8 hours for 4 days. Then they were subjected to the withdrawal of Alcohol for six days and in seventh day divided in 5 groups of 8 rats (1) control (2) Curcumin (3) Swimming training (4) Curcumin and Swimming training (5) sham. Groups 3 and 4 swam 5 sessions per week for 2 weeks and groups 2 and 4 used Curcumin 5 times per week for 2 weeks peritoneally. For statistical analysis of data two-way ANOVA was used (p≤ 0. 05). Results: Swimming training had significant effect on increase of SOD (p=0. 001), GPX (p=0. 001) and TAC (p=0. 009) and reduction of MDA (p=0. 001) and PC (p=0. 001) of rats. Curcumin had significant effect on increase of SOD (p=0. 001) and GPX (p=0. 001) and reduction of MDA (p=0. 001) and PC (p=0. 001) of rats but had no significant effect on TAC (p=0. 34) also Curcumin and Swimming training had interactive effects on increase of SOD (p=0. 001) and GPX (p=0. 001) and reduction of PC (p=0. 009) of rats but had no interactional effect on TAC (p=0. 48) and MDA (p=0. 13). Conclusion: Probably, Swimming training and Curcumin can be applied simultaneously in withdrawal period of Alcohol overdose to increase Antioxidant factors.

Cites

The Effects of Endurance Training and Purslane (Portulaca oleracea) Seed Consumption on Cytochrome-C and Malondialdehyde in the Heart Tissues of Rats Poisoned with H2O2

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APA: Copy

Seyed, A., Farsi, Sirous, HOSSEINI, S.A., & KAKA, GH.. (2018). Antioxidant Effects of Swimming Training and Curcumin in Withdrawal Period of Alcohol Overdose in Rats. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 8(3 ), 901-910. SID. https://sid.ir/paper/203856/en

Vancouver: Copy

Seyed A., Farsi Sirous, HOSSEINI S.A., KAKA GH.. Antioxidant Effects of Swimming Training and Curcumin in Withdrawal Period of Alcohol Overdose in Rats. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2018;8(3 ):901-910. Available from: https://sid.ir/paper/203856/en

IEEE: Copy

A. Seyed, Sirous Farsi, S.A. HOSSEINI, and GH. KAKA, “Antioxidant Effects of Swimming Training and Curcumin in Withdrawal Period of Alcohol Overdose in Rats,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 8, no. 3 , pp. 901–910, 2018, [Online]. Available: https://sid.ir/paper/203856/en

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