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Information Journal Paper

Title

ASSESSMENT OF ASSOCIATION OF A9194G POLYMORPHISM IN THE EXON 4 ENEGSURVIVIN WITH THE GASTRIC CANCER RISK

Author(s)

BAGHERI ZAHRA | MOHAMADYNEJAD PARISA | Moghanibashi mansooriye Mohammad Mehdi | Issue Writer Certificate 

Pages

  97-103

Abstract

 Aim and Background: GASTRIC CANCER is the fourth most common cancer and second leading cause of cancer related death inthe world. SURVIVIN GENE encodes a protein which is one of the APOPTOSIS INHIBITORS. It plays animportant role in maintaining the gastric mucosa and is vital for normal function of the stomach. Italso plays a key role in differentiation of gastric the epithelial cells and repairs the gastric mucosaafter damage. This gene is widely expressed in the gastric stomach, its expression increasesignificantly in GASTRIC CANCER. Regarding role of SURVIVIN GENE in GASTRIC CANCER, in the present study, the association of SINGLE-NUCLEOTIDE POLYMORPHISM (rs2071214) A9194G in exon 4 SURVIVIN GENEwith risk of GASTRIC CANCERs is investigated. Material and methods: In this study, 101 patients with GASTRIC CANCER and 101 healthy subjects as the control (all matched interms of age and gender) were examined by PCR-RFLP technique. The obtained data andinformation were analyzed by statistical regression logestic and2testes. Results: The results of this study showed that different genotypes of polymorphism A9194G and alleles arenot significantly associated with GASTRIC CANCER. Conclusion: Our results have shown that there isn’ t an association between A9194G polymorphism with the riskof GASTRIC CANCER.

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  • Cite

    APA: Copy

    BAGHERI, ZAHRA, MOHAMADYNEJAD, PARISA, & Moghanibashi mansooriye, Mohammad Mehdi. (2017). ASSESSMENT OF ASSOCIATION OF A9194G POLYMORPHISM IN THE EXON 4 ENEGSURVIVIN WITH THE GASTRIC CANCER RISK. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 7(28 ), 97-103. SID. https://sid.ir/paper/204488/en

    Vancouver: Copy

    BAGHERI ZAHRA, MOHAMADYNEJAD PARISA, Moghanibashi mansooriye Mohammad Mehdi. ASSESSMENT OF ASSOCIATION OF A9194G POLYMORPHISM IN THE EXON 4 ENEGSURVIVIN WITH THE GASTRIC CANCER RISK. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2017;7(28 ):97-103. Available from: https://sid.ir/paper/204488/en

    IEEE: Copy

    ZAHRA BAGHERI, PARISA MOHAMADYNEJAD, and Mohammad Mehdi Moghanibashi mansooriye, “ASSESSMENT OF ASSOCIATION OF A9194G POLYMORPHISM IN THE EXON 4 ENEGSURVIVIN WITH THE GASTRIC CANCER RISK,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 7, no. 28 , pp. 97–103, 2017, [Online]. Available: https://sid.ir/paper/204488/en

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