EFFECT OF VITAMIN E SUPPLEMENTATION ON LIPID PEROXIDATION AND THE ANTIOXIDANT DEFENSE RESPONSES FOLLOWING AN EXHAUSTING AEROBIC EXERCISE

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CHOOBINEH S.; AKBARZADEH H.; NAGHIZADEH H.

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Journal: Tibbi- i- kar Year:2014 | Volume:6 | Issue:2 Page(s): 32-43

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Title

EFFECT OF VITAMIN E SUPPLEMENTATION ON LIPID PEROXIDATION AND THE ANTIOXIDANT DEFENSE RESPONSES FOLLOWING AN EXHAUSTING AEROBIC EXERCISE

Author(s)

CHOOBINEH S. | AKBARZADEH H. | NAGHIZADEH H. | Issue Writer Certificate

Keywords

VITAMIN EQ2

TOTAL ANTIOXIDANT CAPACITYQ2

CONTINUOUS AEROBIC EXERCISEQ2

OXIDATIVE STRESSQ2

Abstract

Background: physical exercise could induce lipid peroxidation as a result of OXIDATIVE STRESS. And intake of antioxidant compound may alleviate this stress by enhancing antioxidant defense. This study aimed to investigate the effect of VITAMIN E supplementation as an antioxidant on the lipid peroxidation and serum TOTAL ANTIOXIDANT CAPACITY following exhaustive CONTINUOUS AEROBIC EXERCISE in wistar rats.Methods: 28 wistar rats aged 4 month were assigned randomly into one of 4 groups: rest, rest VITAMIN E, CONTINUOUS AEROBIC EXERCISE, and CONTINUOUS AEROBIC EXERCISE-VITAMIN E. The supplement groups, were administrated a dose of 250 IU per one kilogram of daily intake food for one month of supplementation. All groups were subjected a familiarization treadmill protocol for two weeks. Finally, rats in CONTINUOUS AEROBIC EXERCISE groups exercised at 70% vo2 max. The running speed was 20 m/min at a gradient 5%. Serum malon dealdehyde (MDA) and TOTAL ANTIOXIDANT CAPACITY (TAC) were measured. Data were analyzed by one way ANOVA and sheffe post hoc at P<0.05 level.Results: The MDA increased significantly following CONTINUOUS AEROBIC EXERCISE (P<0.05) but VITAMIN E could not decrease significantly the elevated response of MDA following exercise. However The TAC was higher significantly in continuous aerobic VITAMIN E group compare to the rest group (P<0.01).Conclusion: VITAMIN E supplementation despite of enhancement of the antioxidant capacity cannot prevent lipid peroxidation following CONTINUOUS AEROBIC EXERCISE in wistar rats.

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APA: Copy

CHOOBINEH, S., AKBARZADEH, H., & NAGHIZADEH, H.. (2014). EFFECT OF VITAMIN E SUPPLEMENTATION ON LIPID PEROXIDATION AND THE ANTIOXIDANT DEFENSE RESPONSES FOLLOWING AN EXHAUSTING AEROBIC EXERCISE. OCCUPATIONAL MEDICINE, 6(2), 32-43. SID. https://sid.ir/paper/207076/en

Vancouver: Copy

CHOOBINEH S., AKBARZADEH H., NAGHIZADEH H.. EFFECT OF VITAMIN E SUPPLEMENTATION ON LIPID PEROXIDATION AND THE ANTIOXIDANT DEFENSE RESPONSES FOLLOWING AN EXHAUSTING AEROBIC EXERCISE. OCCUPATIONAL MEDICINE[Internet]. 2014;6(2):32-43. Available from: https://sid.ir/paper/207076/en

IEEE: Copy

S. CHOOBINEH, H. AKBARZADEH, and H. NAGHIZADEH, “EFFECT OF VITAMIN E SUPPLEMENTATION ON LIPID PEROXIDATION AND THE ANTIOXIDANT DEFENSE RESPONSES FOLLOWING AN EXHAUSTING AEROBIC EXERCISE,” OCCUPATIONAL MEDICINE, vol. 6, no. 2, pp. 32–43, 2014, [Online]. Available: https://sid.ir/paper/207076/en

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