COMPARING THE EFFECT OF HYDROXY ETHYL STARCH WITH CRYSTALLOIDS ON HEMODYNAMIC CHANGES FOLLOWING SPINAL ANESTHESIA IN CAESAREAN SECTION

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ALIMIAN MAHZAD; MOHSENI MASOUD; SAFAEIAN REZA; AZAD MAJEDI MOHAMMAD

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Journal: Journal of Anesthesiology and Pain Year:2014 | Volume:4 | Issue:3 Page(s): 4-10

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Title

COMPARING THE EFFECT OF HYDROXY ETHYL STARCH WITH CRYSTALLOIDS ON HEMODYNAMIC CHANGES FOLLOWING SPINAL ANESTHESIA IN CAESAREAN SECTION

Author(s)

ALIMIAN MAHZAD | MOHSENI MASOUD | SAFAEIAN REZA | AZAD MAJEDI MOHAMMAD | Issue Writer Certificate

Keywords

CAESARIAN SECTIONQ3

HYDROXY ETHYL STARCHQ2

CRYSTALLOIDQ2

SPINAL ANESTHESIAQ3

BLOOD PRESSUREQ3

Abstract

Aim and Background: Although controversial, many studies have shown effectiveness of colloid loading as a substitute for CRYSTALLOIDs on reducing the incidence of hypotension in SPINAL ANESTHESIA. This study was conducted to compare the effects of three intravenous fluid regimens on hemodynamic changes following SPINAL ANESTHESIA in cesarean section. The regimens included 6% HYDROXY ETHYL STARCH 130.0.4 (HES) as a colloid and two CRYSTALLOIDs (lactated ringer’s solution and sodium chloride 0.9%).Methods and Materials: In a double-blind clinical trial, 90 otherwise healthy parturients candidate for elective caesarean section, were randomly allocated to receive lactated ringer’s solution (1000 ml), sodium chloride 0.9% (1000 ml) or HES (7.5 mL/Kg) as preloading before SPINAL ANESTHESIA. Hemodynamic parameters including BLOOD PRESSURE and heart rate, umbilical cord blood pH and the neonatal Apgar score were compared among the three groups.Findings: There was no difference in the basic hemodynamic measurements among the three groups. The incidence of hypotension and the required dose of ephedrine were lower in HES group (p=0.008). There was no significant difference in umbilical cord blood PH or Apgar scores among the intervention groups. Conclusions: Preloading with HES is more effective than CRYSTALLOIDs in preventing hypotension after SPINAL ANESTHESIA without leading to a significant difference in Apgar score and umblical cord blood pH.

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APA: Copy

ALIMIAN, MAHZAD, MOHSENI, MASOUD, SAFAEIAN, REZA, & AZAD MAJEDI, MOHAMMAD. (2014). COMPARING THE EFFECT OF HYDROXY ETHYL STARCH WITH CRYSTALLOIDS ON HEMODYNAMIC CHANGES FOLLOWING SPINAL ANESTHESIA IN CAESAREAN SECTION. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 4(3), 4-10. SID. https://sid.ir/paper/216268/en

Vancouver: Copy

ALIMIAN MAHZAD, MOHSENI MASOUD, SAFAEIAN REZA, AZAD MAJEDI MOHAMMAD. COMPARING THE EFFECT OF HYDROXY ETHYL STARCH WITH CRYSTALLOIDS ON HEMODYNAMIC CHANGES FOLLOWING SPINAL ANESTHESIA IN CAESAREAN SECTION. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2014;4(3):4-10. Available from: https://sid.ir/paper/216268/en

IEEE: Copy

MAHZAD ALIMIAN, MASOUD MOHSENI, REZA SAFAEIAN, and MOHAMMAD AZAD MAJEDI, “COMPARING THE EFFECT OF HYDROXY ETHYL STARCH WITH CRYSTALLOIDS ON HEMODYNAMIC CHANGES FOLLOWING SPINAL ANESTHESIA IN CAESAREAN SECTION,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 4, no. 3, pp. 4–10, 2014, [Online]. Available: https://sid.ir/paper/216268/en

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