COMPARISON OF POST-OPERATIVE PAIN IN PATIENTS WITH LEG FRACTURE SURGERY WITH CELECOXIB ADMINISTRATION IN DIFFERENT PREOPERATIVE TIMES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

POURNAJAFIAN ALI REZA; SEHAT MALIHE; GHODRATI MOHAMMAD REZA; ROKHTABNAK FARANAK; KHOLDBARIN ALIREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Anesthesiology and Pain Year:2011 | Volume:1 | Issue:4 Page(s): 61-71

Download Full-Text

Persian Verion

View:

1,076

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF POST-OPERATIVE PAIN IN PATIENTS WITH LEG FRACTURE SURGERY WITH CELECOXIB ADMINISTRATION IN DIFFERENT PREOPERATIVE TIMES

Author(s)

Keywords

CELECOXIBQ2

POST-OPERATIVE PAINQ3

LEG FRACTUREQ2

SPINAL ANESTHESIAQ3

Abstract

Background: Efficacy of preoperative oral administration of CELECOXIB to prevent postoperative pain has been proved in several studies. Also some studies were done about efficient and enough dose to control postoperative pain but there is no agreement about administration in one single dose or administration in short divided doses. In this study, we conducted to evaluate the clinical efficacy of two different doses (200 mg and 400 mg) of CELECOXIB, as selective cyclooxygenase-2 inhibitors, on acute pain severity after orthopedic surgeries.Methods: In this randomized clinical trial, 60 patients candidate LEG FRACTURE fixation under SPINAL ANESTHESIA were enrolled. After taking informed consent, The patients were assigned randomly between three groups (group A: 400 mg at night before surgery, group B: 200 mg night before surgery and 200 mg in the morning and group C: no premedication). The severity of pain was evaluated by VAS (visual analogue scale), the time of anlgesic request by the patient and amounts of opioids administered during 24 hours after surgery was recorded and compared.Results: There was no statistically significant difference between three groups regarding to age, sex, and duration of operation time. The mean pain severity after 6 hours (post-operation) was the same in three groups. The mean of time of analgesic request after operation was 196.5±121 minute in patients receiving 400 mg CELECOXIB in which it was significantly greater than the others (p=0.01). the mean of opioid consumption in patients receiving 400 mg CELECOXIB was less than the other groups but it didn’t show any significant difference.Conclusion: Our study showed that administration of 400 mg CELECOXIB single dose was effective to postpone time of opioid request after LEG FRACTURE operation under SPINAL ANESTHESIA, but in comparison with two divided doses of 200 mg CELECOXIB, it didn’t have any significant difference on postoperative severity of pain. Also single dose (400mg) reduced the amounts of opioid consumption compared to two divided 200mg dose.

Cites

No record.

References

No record.

Cite

APA: Copy

POURNAJAFIAN, ALI REZA, SEHAT, MALIHE, GHODRATI, MOHAMMAD REZA, ROKHTABNAK, FARANAK, & KHOLDBARIN, ALIREZA. (2011). COMPARISON OF POST-OPERATIVE PAIN IN PATIENTS WITH LEG FRACTURE SURGERY WITH CELECOXIB ADMINISTRATION IN DIFFERENT PREOPERATIVE TIMES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 1(4), 61-71. SID. https://sid.ir/paper/216322/en

Vancouver: Copy

POURNAJAFIAN ALI REZA, SEHAT MALIHE, GHODRATI MOHAMMAD REZA, ROKHTABNAK FARANAK, KHOLDBARIN ALIREZA. COMPARISON OF POST-OPERATIVE PAIN IN PATIENTS WITH LEG FRACTURE SURGERY WITH CELECOXIB ADMINISTRATION IN DIFFERENT PREOPERATIVE TIMES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2011;1(4):61-71. Available from: https://sid.ir/paper/216322/en

IEEE: Copy

ALI REZA POURNAJAFIAN, MALIHE SEHAT, MOHAMMAD REZA GHODRATI, FARANAK ROKHTABNAK, and ALIREZA KHOLDBARIN, “COMPARISON OF POST-OPERATIVE PAIN IN PATIENTS WITH LEG FRACTURE SURGERY WITH CELECOXIB ADMINISTRATION IN DIFFERENT PREOPERATIVE TIMES,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 1, no. 4, pp. 61–71, 2011, [Online]. Available: https://sid.ir/paper/216322/en

Related Journal Papers