EVALUATION OF ORAL CLONIDINE EFFECTS ON PREVENTION OF POST-ANESTHESIA SHIVERING

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IMANI FARSAD; ETEZADI FARHAD; KHAJAVI MOHAMMAD REZA; SHARIAT MOHARARI REZA; NAJAFI ATABAK

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Journal: Journal of Anesthesiology and Pain Year:2012 | Volume:2 | Issue:7 Page(s): 96-101

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Title

EVALUATION OF ORAL CLONIDINE EFFECTS ON PREVENTION OF POST-ANESTHESIA SHIVERING

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Keywords

ANESTHESIA (GENERAL)Q3

CLONIDINEQ3

SHIVERINGQ2

Abstract

Aim and Background: SHIVERING is a common post anesthesia complication. Intravenous CLONIDINE administration at induction of anesthesia is a useful drug for decreasing of incidence and severity of post-anesthesia SHIVERING. As CLONIDINE injection can induce side effects therefore we evaluated the oral CLONIDINE premedication on post-anesthesia SHIVERING.Methods and Materials: In a RCT, 60 adult patients in ASA class 1 & 2 scheduled for cholecystectomy were assigned to 2 groups.2 hours before anesthesia, 0.2 mg oral CLONIDINE was administrated and to the other group placebo was administered. Surgery room temperature was adjusted for 21-23oc. At the end of the anesthesia, the patients' SHIVERING was evaluated in the recovery room by "Crossley & Mahajan SHIVERING score".Findings: There was no difference at decrease of SpO2 & H.R. & MAP between 2 groups. There was no difference in average time of emergence between 2 groups. Overall 75% of the patients shivered after anesthesia. Median SHIVERING score in CLONIDINE group was 1.97 and in placebo were 2.87. It became revealed that there was clear difference at SHIVERING score between 2 groups (less severe or generalized SHIVERING patients in test group).Conclusions: 0.2 mg CLONIDINE tablet, 2 hours before anesthesia is similar to injecting drug and is effective in prevention of post-anesthesia SHIVERING but its complication is less. Lack of difference at hemodynamics & SpO2 & emergence in our study may be due to slow absorption of oral CLONIDINE.

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APA: Copy

IMANI, FARSAD, ETEZADI, FARHAD, KHAJAVI, MOHAMMAD REZA, SHARIAT MOHARARI, REZA, & NAJAFI, ATABAK. (2012). EVALUATION OF ORAL CLONIDINE EFFECTS ON PREVENTION OF POST-ANESTHESIA SHIVERING. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 2(7), 96-101. SID. https://sid.ir/paper/216338/en

Vancouver: Copy

IMANI FARSAD, ETEZADI FARHAD, KHAJAVI MOHAMMAD REZA, SHARIAT MOHARARI REZA, NAJAFI ATABAK. EVALUATION OF ORAL CLONIDINE EFFECTS ON PREVENTION OF POST-ANESTHESIA SHIVERING. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2012;2(7):96-101. Available from: https://sid.ir/paper/216338/en

IEEE: Copy

FARSAD IMANI, FARHAD ETEZADI, MOHAMMAD REZA KHAJAVI, REZA SHARIAT MOHARARI, and ATABAK NAJAFI, “EVALUATION OF ORAL CLONIDINE EFFECTS ON PREVENTION OF POST-ANESTHESIA SHIVERING,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 2, no. 7, pp. 96–101, 2012, [Online]. Available: https://sid.ir/paper/216338/en

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