COMPARISON OF THE ANALGESIC EFFECT OF CELEBREX VS. IBUPROFEN ON POST ENDODONTIC PAIN

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PARTOVI M.; MOGHADAM NIA A.K.; PEIRAVI A.H.

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Journal: Journal of Dental School Year:2005 | Volume:23 | Issue:1 Page(s): 1-10

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Title

COMPARISON OF THE ANALGESIC EFFECT OF CELEBREX VS. IBUPROFEN ON POST ENDODONTIC PAIN

Author(s)

PARTOVI M. | MOGHADAM NIA A.K. | PEIRAVI A.H. | Issue Writer Certificate

Keywords

PAINQ2

ENDODONTIC TREATMENTQ3

CELEBREXQ4

IBUPROFENQ4

Abstract

Purpose: PAIN control before and after ENDODONTIC TREATMENT is always a major concern in dentistry. Non-steroidal anti inflammatory drugs (NSAIDs) are the most common drugs prescribed for preventive and post operative PAIN control in root canal therapy. During the last decade a new generation of NSAIDs has been introduced and it seems that because of its selective inhibition of cyclooxgenase-2 activity, these drugs have less side effects than other common NSAIDs. Since no studies have been performed to compare the new NSAIDs analgesic effect with other NSAIDs in patients undergoing ENDODONTIC TREATMENT, therefore a randomized double blind study was accomplished to compare the analgesic effect of CELEBREX (selective cox-2 inhibitor) and IBUPROFEN on postendodontic PAIN. The aim of this study was to compare the analgesic effect of CELEBREX vs IBUPROFEN on post endodontic PAIN. Methods & Materials: In a randomized double blind clinical trial study 40 patients with moderate to severe endodontic PAIN underwent pulpectomy and received either IBUPROFEN( every 6 hours) or CELEBREX( every 12 hours) for 3 days after ENDODONTIC TREATMENT. Patient-reported visual analog scale rating of PAIN intensity was conducted upon initial clinical presentation and at 6, 24, 36, 48, and 60h after completion of pulpectomy. Also, patients were asked to record the side affects in the questionnaires. The results were obtained using the Mann Whitney, t and Chi- square tests by using the SPSS software. Results: The results showed that there was no significant difference between analgesic effect of CELEBREX and IBUPROFEN in controlling PAIN at all periods of time after ENDODONTIC TREATMENT (P>0.05). Conclusion: According to the results, CELEBREX because of its high cost, no effective PAIN control and similar incidence of side effects in comparison to IBUPROFEN is not a drug of choice for short term PAIN control in endodontics.

Cites

HISTOPATHOLOGIC STUDY OF THE EFFECT OF CELECOXIB TO CONTROL ACUTE PERIAPICAL INFLAMMATION AFTER ROOT CANAL TREATMENT IN CATS

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APA: Copy

PARTOVI, M., MOGHADAM NIA, A.K., & PEIRAVI, A.H.. (2005). COMPARISON OF THE ANALGESIC EFFECT OF CELEBREX VS. IBUPROFEN ON POST ENDODONTIC PAIN. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 23(1), 1-10. SID. https://sid.ir/paper/21852/en

Vancouver: Copy

PARTOVI M., MOGHADAM NIA A.K., PEIRAVI A.H.. COMPARISON OF THE ANALGESIC EFFECT OF CELEBREX VS. IBUPROFEN ON POST ENDODONTIC PAIN. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2005;23(1):1-10. Available from: https://sid.ir/paper/21852/en

IEEE: Copy

M. PARTOVI, A.K. MOGHADAM NIA, and A.H. PEIRAVI, “COMPARISON OF THE ANALGESIC EFFECT OF CELEBREX VS. IBUPROFEN ON POST ENDODONTIC PAIN,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 23, no. 1, pp. 1–10, 2005, [Online]. Available: https://sid.ir/paper/21852/en

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