THE EFFECT OF AEROBIC EXERCISE AFTER CARBON BLACK EXPOSURE ON TLR4 AND TLR2 GENE EXPRESSION IN HIPPOCAMPUS TISSUE OF WISTAR RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

REZAEE SERAJI BATOOL; AGHA ALINEJAD HAMID; EBTEKAR MASOUMEH; GHARAKHNLOO REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Sport Physiology and Management Investigations Year:2018 | Volume:10 | Issue:1 Page(s): 23-33

Download Full-Text

Persian Verion

View:

1,001

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF AEROBIC EXERCISE AFTER CARBON BLACK EXPOSURE ON TLR4 AND TLR2 GENE EXPRESSION IN HIPPOCAMPUS TISSUE OF WISTAR RATS

Author(s)

REZAEE SERAJI BATOOL | AGHA ALINEJAD HAMID | EBTEKAR MASOUMEH | GHARAKHNLOO REZA | Issue Writer Certificate

Keywords

AEROBIC EXERCISEQ1

AIR POLLUTIONQ2

TLR4Q1

TLR2Q1

Abstract

Exposure to AIR POLLUTION affects central nervous system and leads to neuroinflammation and neurodegeneration. The aim of this study was to evaluate the effect of AEROBIC EXERCISE and carbon black exposure on TLR4 and TLR2 mRNA gene expression in the hippocampus of rats.24 male Wistar rats were randomly assigned to 4 groups: A: control, B: exposure to pollution, C: exercise, D: exercise-pollution. B and D groups were exposed to PM10 carbon black for 4 weeks. The D and C groups carried out AEROBIC EXERCISE program with 50% of their own maximal speed (60 minutes per session) after each session of pollution. The mRNA gene expression of TLR4 and TLR2 were analyzed in hippocampus tissue of rats by Real time – PCR. In order to determine the significance of the effect of exercise and pollution, two-way ANOVA test was used. Carbon black AIR POLLUTION significantly increased TLR4 (P=0.005) and TLR2 (P=0.033) mRNA gene expression. The exercise had no significant effect on the mRNA gene expression of TLR4 (P=0.137) and TLR2 (P=0.113). The exercise following an exposure to polluted air had no significant effect on mRNA gene expression of TLR4 (P=0.063) and TLR2 (P=0.867) in hippocampus tissue of male rats. Also, the exercise was associated with a significant decrease in body mass in carbon black exposed groups. It seems that AEROBIC EXERCISE reduces TLR4 and TLR2 in hippocampus tissue of rats after an exposure to polluted air and may be able to moderate the neuroinflammatory effects resulted from pollution.

Cites

No record.

References

ASSESSING PUBLIC HEALTH BURDEN ASSOCIATED WITH EXPOSURE TO AMBIENT BLACK CARBON IN THE UNITED STATES

Cite

APA: Copy

REZAEE SERAJI, BATOOL, AGHA ALINEJAD, HAMID, EBTEKAR, MASOUMEH, & GHARAKHNLOO, REZA. (2018). THE EFFECT OF AEROBIC EXERCISE AFTER CARBON BLACK EXPOSURE ON TLR4 AND TLR2 GENE EXPRESSION IN HIPPOCAMPUS TISSUE OF WISTAR RATS. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, 10(1 ), 23-33. SID. https://sid.ir/paper/222296/en

Vancouver: Copy

REZAEE SERAJI BATOOL, AGHA ALINEJAD HAMID, EBTEKAR MASOUMEH, GHARAKHNLOO REZA. THE EFFECT OF AEROBIC EXERCISE AFTER CARBON BLACK EXPOSURE ON TLR4 AND TLR2 GENE EXPRESSION IN HIPPOCAMPUS TISSUE OF WISTAR RATS. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS[Internet]. 2018;10(1 ):23-33. Available from: https://sid.ir/paper/222296/en

IEEE: Copy

BATOOL REZAEE SERAJI, HAMID AGHA ALINEJAD, MASOUMEH EBTEKAR, and REZA GHARAKHNLOO, “THE EFFECT OF AEROBIC EXERCISE AFTER CARBON BLACK EXPOSURE ON TLR4 AND TLR2 GENE EXPRESSION IN HIPPOCAMPUS TISSUE OF WISTAR RATS,” SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, vol. 10, no. 1 , pp. 23–33, 2018, [Online]. Available: https://sid.ir/paper/222296/en

Related Journal Papers