THE EFFECT OF FOLATE SUPPLEMENTATION DURING 10 WEEKS OF RESISTANCE TRAINING ON SERUM AND STOMACH LEVEL OF GHRELIN AND SERUM LEVEL OF INSULIN IN MALE WISTAR RATS

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GORZI A.; GHANBARI N.

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Journal: SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE) Year:2017 | Volume:9 | Issue:33 Page(s): 87-100

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Title

THE EFFECT OF FOLATE SUPPLEMENTATION DURING 10 WEEKS OF RESISTANCE TRAINING ON SERUM AND STOMACH LEVEL OF GHRELIN AND SERUM LEVEL OF INSULIN IN MALE WISTAR RATS

Author(s)

GORZI A. | GHANBARI N. | Issue Writer Certificate

Keywords

HIGH INTENSITY RESISTANCE TRAININGQ1

FOLATE SUPPLEMENTATIONQ1

GHRELINQ2

INSULINQ2

APPETITEQ2

Abstract

The purpose of this study was to investigate the effect of FOLATE SUPPLEMENTATION during 10 weeks of resistance training on serum and stomach level of GHRELIN and serum level of INSULIN in male Wistar rats. Thirty-two male Wistar rats (8 weeks old, 204.4±18.2 g.BW) after 1 week familiarization and based on their weights, were randomly divided into four equal groups (8 rats in each group): control, FOLATE SUPPLEMENTATION, resistance training, resistance + supplementation groups. Training groups carried out 10 weeks (5 session/week) of resistance training on 1 meter height ladder (divided by 26 stairs) with load corresponding to30℅ of their body weight (suspended from tail) at the first week and was gradually increased to 250℅ at the last week. Supplementation was conducted by dissolving 10 mg folic acid in per liter of consumed water. Forty-eight hours following last session of training, animals were anesthetized, sacrificed and their gastric tissues and serums were collected. Serum concentrations of GHRELIN and INSULIN and stomach concentrations of GHRELIN were assessed using ELISA method and analyzed by ANOVA and kruskal vallis tests (P<0.05). The results showed that serum level of GHRELIN in resistance group decreased significantly in compare with control (P=0.002), supplementation (P=0.001) and resistance + supplementation (P=0.017) groups. Also, the GHRELIN of stomach increased significantly in resistance + supplementation group in compare with control (P=0.014) and resistance (P=0.017) groups. There was no significant differences between 4 groups in serum INSULIN (P=0.673). Based on our results, FOLATE SUPPLEMENTATION during resistance training increases the GHRELIN of stomach or at least prevents from decreases the serum GHRELIN.

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APA: Copy

GORZI, A., & GHANBARI, N.. (2017). THE EFFECT OF FOLATE SUPPLEMENTATION DURING 10 WEEKS OF RESISTANCE TRAINING ON SERUM AND STOMACH LEVEL OF GHRELIN AND SERUM LEVEL OF INSULIN IN MALE WISTAR RATS. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), 9(33 ), 87-100. SID. https://sid.ir/paper/228270/en

Vancouver: Copy

GORZI A., GHANBARI N.. THE EFFECT OF FOLATE SUPPLEMENTATION DURING 10 WEEKS OF RESISTANCE TRAINING ON SERUM AND STOMACH LEVEL OF GHRELIN AND SERUM LEVEL OF INSULIN IN MALE WISTAR RATS. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE)[Internet]. 2017;9(33 ):87-100. Available from: https://sid.ir/paper/228270/en

IEEE: Copy

A. GORZI, and N. GHANBARI, “THE EFFECT OF FOLATE SUPPLEMENTATION DURING 10 WEEKS OF RESISTANCE TRAINING ON SERUM AND STOMACH LEVEL OF GHRELIN AND SERUM LEVEL OF INSULIN IN MALE WISTAR RATS,” SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), vol. 9, no. 33 , pp. 87–100, 2017, [Online]. Available: https://sid.ir/paper/228270/en

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