The purpose of this study was to compare effects of three combined aerobic-resistance exercise training protocols with different intensities on adiponectin, retinol binding protein4 and lipid profile in men with type 2diabetes.43male patients with type2 diabetes were randomly divided into 4groups (three combined aerobic-resistance exercise training groups 1 (Age 47.3±9.0, Weight 77.1±9.1, BMI 26.6±3.5), 2 (Age 45.6±8.3, Weight 80.6±8.7, BMI 26.9±1.8), 3 (Age 47.0±5.9, Weight 82.9±11.7, BMI 28.0±2.9) and control (Age 46.1±9.2, Weight 84.4±10.3, BMI 28.2±2.4)). Training groups performed combined aerobic-resistance exercises for 12 weeks, 3 times a week with given intensities) group 1: resistance 50-60% one repetition maximum- aerobic 70-80% maximum heart rate, group 2: resistance 60-70% one repetition maximum- aerobic 60-70% maximum heart rate and group 3: resistance 70-80% one repetition maximum- aerobic 50-60% maximum heart rate). The blood sampling to determine the levels of adiponectin, retinol binding protein 4 and lipid profile before and after 12 weeks, were conducted. Data were analyzed using analysis of covariance. Retinol binding protein 4 levels significantly decreased in 2 and 3 combined training groups compared with control group (P<0.05). Triglyceride levels was significantly decreased in all training groups (P<0.05). No significant difference were observed between groups in body weight, Body mass index, fat mass, adiponectin, cholesterol, High Density Lipoprotein Cholesterol and Low Density Lipoprotein-Cholesterol.12weeks of combined aerobic-resistance exercise training protocols with different intensities has no significant effect on adiponectin and anthropometric indices. But, two combined exercise training protocols of 2 and 3 through decreasing retinol binding protein 4 and triglyceride levels could be helpful on improvement of metabolic disorders in patient with type 2 diabetes.