THE EFFECT OF IMMOBILIZATION AND SURGERY STRESS ON SERUM GHRELIN LEVEL, BODY WEIGHT, AND FOOD CONSUMPTION IN MALE RATS

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ZAREIAN P.; MOZAFAR A.; KARGAR JAHROMI H.

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Journal: Ebnesina Year:2015 | Volume:17 | Issue:3 (52) Page(s): 5-10

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Title

THE EFFECT OF IMMOBILIZATION AND SURGERY STRESS ON SERUM GHRELIN LEVEL, BODY WEIGHT, AND FOOD CONSUMPTION IN MALE RATS

Author(s)

ZAREIAN P. | MOZAFAR A. | KARGAR JAHROMI H. | Issue Writer Certificate

Keywords

PHYSIOLOGICAL STRESSESQ2

OPERATIVE SURGICAL PROCEDURESQ2

IMMOBILIZATIONQ2

GHRELINQ2

BODY WEIGHTQ2

Abstract

Background: In our daily life, we encounter with various types of stress. These stresses result to different autonomic, hormonal, and behavioral responses. One of the hormones that its secretion is affected by stress is called GHRELIN. The aim of this study was to investigate the effect of IMMOBILIZATION and surgery stress on serum GHRELIN level, food consumption, and BODY WEIGHT in male rats.Materials and methods: Forty Sprague Dawley male rats (200-220 g weight) were used. The serum GHRELIN level (via Elisa method), food consumption (with daily measurement), and changes in BODY WEIGHT (in seven days) were measured following the surgery and IMMOBILIZATION stress. Also, BODY WEIGHT was measured in the first and 7thday.Results: Compared to the control group, IMMOBILIZATION stress caused a significant increase in the level of serum GHRELIN (56.8±8.5vs. 31.7±3.7pg/ml and food consumption (371.3 vs. 287±11 g). The increase of BODY WEIGHT was lower than the control group (2.3±1 vs. 12±2 g). It was interesting to note that the surgical stress had no significant effect on the serum GHRELIN level, food consumption, and BODY WEIGHT.Conclusion: In this work, only the stress of IMMOBILIZATION caused a significant change on the serum GHRELIN level, food consumption, and BODY WEIGHT; so it seems that the effect of stress on these factors depends on the kind of stress.

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References

EFFECT OF SURGERY STRESS AND IMMOBILIZATION STRESS ON GHRELIN HORMONE LEVEL, BODY WEIGHT AND FOOD INTAKE IN FEMALE RATS

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APA: Copy

ZAREIAN, P., MOZAFAR, A., & KARGAR JAHROMI, H.. (2015). THE EFFECT OF IMMOBILIZATION AND SURGERY STRESS ON SERUM GHRELIN LEVEL, BODY WEIGHT, AND FOOD CONSUMPTION IN MALE RATS. EBNESINA, 17(3 (52)), 5-10. SID. https://sid.ir/paper/228560/en

Vancouver: Copy

ZAREIAN P., MOZAFAR A., KARGAR JAHROMI H.. THE EFFECT OF IMMOBILIZATION AND SURGERY STRESS ON SERUM GHRELIN LEVEL, BODY WEIGHT, AND FOOD CONSUMPTION IN MALE RATS. EBNESINA[Internet]. 2015;17(3 (52)):5-10. Available from: https://sid.ir/paper/228560/en

IEEE: Copy

P. ZAREIAN, A. MOZAFAR, and H. KARGAR JAHROMI, “THE EFFECT OF IMMOBILIZATION AND SURGERY STRESS ON SERUM GHRELIN LEVEL, BODY WEIGHT, AND FOOD CONSUMPTION IN MALE RATS,” EBNESINA, vol. 17, no. 3 (52), pp. 5–10, 2015, [Online]. Available: https://sid.ir/paper/228560/en

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