THE PREVENTATIVE ROLE OF SESAME OIL ON PHLEBITIS INDUCED BY ANTI-NEOPLASTIC AGENTS

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NEKUZAD N.; ASHK TORAB T.; MOJAB F.; ALAVI H.; AZADEH P.

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Journal: Ebnesina Year:2011 | Volume:14 | Issue:1-2 (39-40) Page(s): 10-16

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Title

THE PREVENTATIVE ROLE OF SESAME OIL ON PHLEBITIS INDUCED BY ANTI-NEOPLASTIC AGENTS

Author(s)

Keywords

SESAME OILQ4

PROPHYLAXISQ3

PHLEBITISQ4

CHEMOTHERAPYQ4

Abstract

Background: PHLEBITIS is an inflammatory response to intravenously injected CHEMOTHERAPY drugs and the reported incidence is about 70% among colorectal cancer patients. The purpose of this study was to determine the effect of external use of SESAME OIL (SO) in prevention of CHEMOTHERAPY-induced PHLEBITIS.Materials and Methods: This randomized controlled clinical trial was performed on 60 patients with colon or rectum cancer, who randomly divided in two equal, control & intervention groups.This protocol was used 10 drops of SO every 12 hours, two times a day, from the first day of CHEMOTHERAPY up to the four teenth day, whereas control group received nothing. Data tools included a bipartite questionnaire (demographic Q, clinical Q & Infusion Therapy scale) for measurement of PHLEBITIS.Results: The incidence of PHLEBITIS in intervention group were significantly lower than that in control group (p<0.05). Kaplan–Meier survival analysis showed that the median survival was less than4 days in the intervention and 8 days more in the control. In addition, there was statistically significant difference between grade and incidence of CHEMOTHERAPY-induced PHLEBITIS with SO and control group (p<0.05).Conclusion: This study shows that external use of SO is effective and well tolerated for PROPHYLAXIS from CHEMOTHERAPY- induced PHLEBITIS. Therefore, it can be suggest as a selected Prevention method for reducing the complication.

Cites

EFFECT OF ARNEBIA EUCHROMA POULTICE ON THE PREVENTION OF PERIPHERAL INTRAVENOUS CATHETER-RELATED PHLEBITIS: A RANDOMIZED CLINICAL TRIAL

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APA: Copy

NEKUZAD, N., ASHK TORAB, T., MOJAB, F., ALAVI, H., & AZADEH, P.. (2011). THE PREVENTATIVE ROLE OF SESAME OIL ON PHLEBITIS INDUCED BY ANTI-NEOPLASTIC AGENTS. EBNESINA, 14(1-2 (39-40)), 10-16. SID. https://sid.ir/paper/228633/en

Vancouver: Copy

NEKUZAD N., ASHK TORAB T., MOJAB F., ALAVI H., AZADEH P.. THE PREVENTATIVE ROLE OF SESAME OIL ON PHLEBITIS INDUCED BY ANTI-NEOPLASTIC AGENTS. EBNESINA[Internet]. 2011;14(1-2 (39-40)):10-16. Available from: https://sid.ir/paper/228633/en

IEEE: Copy

N. NEKUZAD, T. ASHK TORAB, F. MOJAB, H. ALAVI, and P. AZADEH, “THE PREVENTATIVE ROLE OF SESAME OIL ON PHLEBITIS INDUCED BY ANTI-NEOPLASTIC AGENTS,” EBNESINA, vol. 14, no. 1-2 (39-40), pp. 10–16, 2011, [Online]. Available: https://sid.ir/paper/228633/en

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