REVIEW: A REVIEW OF THE ROLE OF STATINS IN THE TREATMENT OF HEART FAILURE WITH THE EMPHASIS ON THE OXIDATIVE STRESS

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SALEHIFAR EBRAHIM

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Journal: JOURNAL OF CLINICAL EXCELLENCE Year:2013 | Volume:1 | Issue:1 Page(s): 115-130

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Title

REVIEW: A REVIEW OF THE ROLE OF STATINS IN THE TREATMENT OF HEART FAILURE WITH THE EMPHASIS ON THE OXIDATIVE STRESS

Author(s)

SALEHIFAR EBRAHIM | Issue Writer Certificate

Keywords

STATINQ2

ATHEROSCLEROSISQ2

HEART FAILUREQ2

OXIDATIVEQ2

Abstract

Cholesterol reduction by STATINs improves the survival of patients with the atherosclerotic cardiovascular diseases, though serum cholesterol level is normal or borderline.In some studies, STATINs have been administered to the HEART FAILURE patients irrespective of their ATHEROSCLEROSIS state or LDL-levels. STATINs may have favorable effects on the OXIDATIVE stress and the cardiac remodeling process. Due to the contradictory results of the studies, this review will briefly discuss the role of OXIDATIVE stress and inflammation in the HEART FAILURE, and then the effects of STATINs on the inflammatory mediators involved in the HEART FAILURE and the clinical trials assigned to the role of STATINs in the management of HEART FAILURE. Finally, considering the methodology of clinical trials, recommendations regarding the use of STATINs in HEART FAILURE patients will be presented.

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APA: Copy

SALEHIFAR, EBRAHIM. (2013). REVIEW: A REVIEW OF THE ROLE OF STATINS IN THE TREATMENT OF HEART FAILURE WITH THE EMPHASIS ON THE OXIDATIVE STRESS. JOURNAL OF CLINICAL EXCELLENCE, 1(1), 115-130. SID. https://sid.ir/paper/243968/en

Vancouver: Copy

SALEHIFAR EBRAHIM. REVIEW: A REVIEW OF THE ROLE OF STATINS IN THE TREATMENT OF HEART FAILURE WITH THE EMPHASIS ON THE OXIDATIVE STRESS. JOURNAL OF CLINICAL EXCELLENCE[Internet]. 2013;1(1):115-130. Available from: https://sid.ir/paper/243968/en

IEEE: Copy

EBRAHIM SALEHIFAR, “REVIEW: A REVIEW OF THE ROLE OF STATINS IN THE TREATMENT OF HEART FAILURE WITH THE EMPHASIS ON THE OXIDATIVE STRESS,” JOURNAL OF CLINICAL EXCELLENCE, vol. 1, no. 1, pp. 115–130, 2013, [Online]. Available: https://sid.ir/paper/243968/en

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