IL-17 AND ITS ROLE IN ACUTE AND CHRONIC INFLAMMATORY RESPONSES OF THE AIRWAYS

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HAMIDIAN GHOLAMREZA; YADEGARI MEHDI; MIRDAR HARIJANI SHADMEHR

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Journal: NAFAS JOURNAL Year:2015 | Volume:2 | Issue:1 Page(s): 1-11

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Title

IL-17 AND ITS ROLE IN ACUTE AND CHRONIC INFLAMMATORY RESPONSES OF THE AIRWAYS

Author(s)

HAMIDIAN GHOLAMREZA | YADEGARI MEHDI | MIRDAR HARIJANI SHADMEHR | Issue Writer Certificate

Keywords

INTERLEUKIN-17Q1

INFLAMMATORY RESPONSESQ1

AIRWAYSQ1

NEUTROPHILSQ1

Abstract

IL-17 family is a subset of cytokines that participates in both acute and chronic inflammatory response. IL-17 is an important link between dependent adaptive immune T-cell and innate immune system, especially an inflammatory component in innate immune response. The ability of IL-17 in NEUTROPHILS chemotaxis is responsible for the central role of Th17 in adaptive immune reactions, which in them neutrophil inflammation is a prominent feature. A large accumulation of NEUTROPHILS in AIRWAYS is the salient features of some pathological conditions such as bronchial asthma and chronic obstructive pulmonary diseases (COPD). IL-17A and IL-17F have many common functions, which are necessary for recruitment and activation of NEUTROPHILS, in chemokine induction. Solely, IL-17A is a weak activator of NFkB, however, it is a powerful cytokine in collaboration with other cytokines such as TNF-a, so it can lead to the initiation and development of the pro-inflammatory responses.

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APA: Copy

HAMIDIAN, GHOLAMREZA, YADEGARI, MEHDI, & MIRDAR HARIJANI, SHADMEHR. (2015). IL-17 AND ITS ROLE IN ACUTE AND CHRONIC INFLAMMATORY RESPONSES OF THE AIRWAYS. NAFAS JOURNAL, 2(1), 1-11. SID. https://sid.ir/paper/252076/en

Vancouver: Copy

HAMIDIAN GHOLAMREZA, YADEGARI MEHDI, MIRDAR HARIJANI SHADMEHR. IL-17 AND ITS ROLE IN ACUTE AND CHRONIC INFLAMMATORY RESPONSES OF THE AIRWAYS. NAFAS JOURNAL[Internet]. 2015;2(1):1-11. Available from: https://sid.ir/paper/252076/en

IEEE: Copy

GHOLAMREZA HAMIDIAN, MEHDI YADEGARI, and SHADMEHR MIRDAR HARIJANI, “IL-17 AND ITS ROLE IN ACUTE AND CHRONIC INFLAMMATORY RESPONSES OF THE AIRWAYS,” NAFAS JOURNAL, vol. 2, no. 1, pp. 1–11, 2015, [Online]. Available: https://sid.ir/paper/252076/en

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