COMPARISON OF AGNORS COUNT IN EXFOLIATIVE CYTOLOGY OF NORMAL ORAL MUCOSA IN SMOKERS AND NON- SMOKERS

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SHAHRABI SH.; ABD ELAHI B.; AHADIAN H.; FALAHZADEH H.

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Journal: Journal of Dental Medicine Year:2005 | Volume:18 | Issue:3 (44) Page(s): 51-58

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Title

COMPARISON OF AGNORS COUNT IN EXFOLIATIVE CYTOLOGY OF NORMAL ORAL MUCOSA IN SMOKERS AND NON- SMOKERS

Author(s)

SHAHRABI SH. | ABD ELAHI B. | AHADIAN H. | FALAHZADEH H. | Issue Writer Certificate

Keywords

AGNOR STAININGQ4

ORAL EXFOLIATIVE CYTOLOGYQ4

SMOKINGQ4

NUCLEOLAR ORGANIZER REGIONSQ4

Abstract

Background and Aim: A strong causal relationship exists between cigarette SMOKING and development of oral squamous cell carcinoma, so oral screening using exfoliative cytology has been recommended to facilitate the early diagnosis of cellular alterations in oral mucosa and silver staining (AgNOR technique) has been proven to be of value in the detection of incipient cellular alterations. The purpose of this study was to compare the argyrophilic nucleolar regions (AgNORs) count of cells collected from normal mucosa of cigarette smokers with that obtained from non- smokers. Materials and Methods: In this cross-sectional study, cytologic smears of normal tongue, buccal mucosa and floor of the mouth from 19 smokers and 19 non- smokers were stained for AgNORs. The AgNORs count was established on 100 cells. The count value of groups were compared and analyzed using the Levens, Paired T, Student and Factorial tests. Using P<0.05 as the limit of significance. Results: The AgNORs were round and had a clustered distribution in both groups. The mean AgNORs count was statistically higher in cells of smokers than non- smokers (P<0.05). There was a significant difference between smears from the floor of the mouth and other anatomical sites in both groups. In this study, no correlation was found between AgNORs count and gender. Conclusion: Analysis of AgNORs suggests that there might be a correlation between the SMOKING habit and an increased rate of cellular proliferation in the oral mucosal cells.

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APA: Copy

SHAHRABI, SH., ABD ELAHI, B., AHADIAN, H., & FALAHZADEH, H.. (2005). COMPARISON OF AGNORS COUNT IN EXFOLIATIVE CYTOLOGY OF NORMAL ORAL MUCOSA IN SMOKERS AND NON- SMOKERS . JOURNAL OF DENTAL MEDICINE, 18(3 (44)), 51-58. SID. https://sid.ir/paper/25479/en

Vancouver: Copy

SHAHRABI SH., ABD ELAHI B., AHADIAN H., FALAHZADEH H.. COMPARISON OF AGNORS COUNT IN EXFOLIATIVE CYTOLOGY OF NORMAL ORAL MUCOSA IN SMOKERS AND NON- SMOKERS . JOURNAL OF DENTAL MEDICINE[Internet]. 2005;18(3 (44)):51-58. Available from: https://sid.ir/paper/25479/en

IEEE: Copy

SH. SHAHRABI, B. ABD ELAHI, H. AHADIAN, and H. FALAHZADEH, “COMPARISON OF AGNORS COUNT IN EXFOLIATIVE CYTOLOGY OF NORMAL ORAL MUCOSA IN SMOKERS AND NON- SMOKERS ,” JOURNAL OF DENTAL MEDICINE, vol. 18, no. 3 (44), pp. 51–58, 2005, [Online]. Available: https://sid.ir/paper/25479/en

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