MAY MEASURING OF PLASMA AMYLOID BETA IN HEALTHY SUBJECTS BE USED AS A PROGNOSTIC FACTOR POINTING TO A RISK OF PENDING ALZHEIMER’S DISEASE?

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SEDAGHAT FERESHTEH

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Journal: Neuroscience Journal of Shefaye Khatam Year:2013 | Volume:1 | Issue:2 Page(s): 41-44

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Information Journal Paper

Title

MAY MEASURING OF PLASMA AMYLOID BETA IN HEALTHY SUBJECTS BE USED AS A PROGNOSTIC FACTOR POINTING TO A RISK OF PENDING ALZHEIMER’S DISEASE?

Author(s)

SEDAGHAT FERESHTEH | Issue Writer Certificate

Keywords

AMYLOID BETA-PEPTIDESQ3

ALZHEIMER DISEASEQ2

HIPPOCAMPUSQ3

COGNITIONQ2

LEARNINGQ2

Abstract

Introduction: Disease modifying treatment strategies for Alzheimer’s disease (AD) have led to a severe need for finding biomarkers to be able to establish a reliable diagnosis at a very early stage and also to follow up the patient and their response to therapy. Amyloids b (Ab) which predominate in amyloid plaques constitute one major neuropathologic hallmark in AD, are produced by all types of cells in the central nervous system and almost all cells in peripheral tissues. Increased plasma level of this peptide is reported in prodromal stage of AD, in mild cognitive impairment.Conclusion: Different genetic, imaging and biochemical studies suggest that increased plasma Ab can begin many years before the onset of symptoms in AD, indicating that it does not require preexisting neural abnormalities. It remains to be verified if the proof of plasma Ab in clinically healthy subjects represents a prognostic factor pointing to a risk of pending AD.

Cites

NEUROLOGICAL ALTERATIONS IN COGNITIVE IMPAIRMENT

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APA: Copy

SEDAGHAT, FERESHTEH. (2013). MAY MEASURING OF PLASMA AMYLOID BETA IN HEALTHY SUBJECTS BE USED AS A PROGNOSTIC FACTOR POINTING TO A RISK OF PENDING ALZHEIMER’S DISEASE?. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 1(2), 41-44. SID. https://sid.ir/paper/257932/en

Vancouver: Copy

SEDAGHAT FERESHTEH. MAY MEASURING OF PLASMA AMYLOID BETA IN HEALTHY SUBJECTS BE USED AS A PROGNOSTIC FACTOR POINTING TO A RISK OF PENDING ALZHEIMER’S DISEASE?. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2013;1(2):41-44. Available from: https://sid.ir/paper/257932/en

IEEE: Copy

FERESHTEH SEDAGHAT, “MAY MEASURING OF PLASMA AMYLOID BETA IN HEALTHY SUBJECTS BE USED AS A PROGNOSTIC FACTOR POINTING TO A RISK OF PENDING ALZHEIMER’S DISEASE?,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 1, no. 2, pp. 41–44, 2013, [Online]. Available: https://sid.ir/paper/257932/en

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