DETECTION OF HUMAN HERPES VIRUS TYPE 6 AND VARICELLA ZOSTER VIRUS IN THE URINE OF PATIENTS WITH MULTIPLE SCLEROSIS IN KERMAN PROVINCE, IRAN

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ESMAILI KIMIA; AMINI KUMARSS

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Journal: Neuroscience Journal of Shefaye Khatam Year:2018 | Volume:6 | Issue:3 Page(s): 19-24

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Title

DETECTION OF HUMAN HERPES VIRUS TYPE 6 AND VARICELLA ZOSTER VIRUS IN THE URINE OF PATIENTS WITH MULTIPLE SCLEROSIS IN KERMAN PROVINCE, IRAN

Author(s)

ESMAILI KIMIA | AMINI KUMARSS | Issue Writer Certificate

Keywords

MULTIPLE SCLEROSISQ2

HERPESVIRUS 6Q2

HUMANQ2

MULTIPLEX POLYMERASE CHAIN REACTIONQ2

AUTOIMMUNITYQ2

Abstract

Introduction: MULTIPLE SCLEROSIS (MS) is a demyelinating disease of the CNS in which AUTOIMMUNITY to myelin plays a role in pathogenesis. Infection with common viruses, particularly varicella zoster virus (VZV) and HUMAN HERPESVIRUS 6 (HHV-6) are postulated to contribute to the pathobiology of MS. The aim of this study was to detect of HHV-6 and VZV in the urine samples of patients with MS in the Kerman province, Iran.Materials and Methods: In this cross-sectional study, a total of 60 non-repetitive urine samples from patients with MS and 60 urine samples from healthy people without any neurological disease and urinary tract infection were collected. The infection with HHV- 6 and VZV were investigated using multiplex PCR method.Results: Of the 60 urine samples obtained from MS patients, 23 (13.8%) and 7 (4.2%) were positive for HHV-6 and VZV, respectively. VZV and HHV-6 were not detected simultaneously in any of obtained samples. HHV-6 and VZV were not found in any samples obtained from healthy people.Conclusion: The prevalence of HHV-6 and VZV viruses in MS patients is high, which may suggest an association between MS and the presence of these viruses in this region.

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APA: Copy

ESMAILI, KIMIA, & AMINI, KUMARSS. (2018). DETECTION OF HUMAN HERPES VIRUS TYPE 6 AND VARICELLA ZOSTER VIRUS IN THE URINE OF PATIENTS WITH MULTIPLE SCLEROSIS IN KERMAN PROVINCE, IRAN. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 6(3 ), 19-24. SID. https://sid.ir/paper/258104/en

Vancouver: Copy

ESMAILI KIMIA, AMINI KUMARSS. DETECTION OF HUMAN HERPES VIRUS TYPE 6 AND VARICELLA ZOSTER VIRUS IN THE URINE OF PATIENTS WITH MULTIPLE SCLEROSIS IN KERMAN PROVINCE, IRAN. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2018;6(3 ):19-24. Available from: https://sid.ir/paper/258104/en

IEEE: Copy

KIMIA ESMAILI, and KUMARSS AMINI, “DETECTION OF HUMAN HERPES VIRUS TYPE 6 AND VARICELLA ZOSTER VIRUS IN THE URINE OF PATIENTS WITH MULTIPLE SCLEROSIS IN KERMAN PROVINCE, IRAN,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 6, no. 3 , pp. 19–24, 2018, [Online]. Available: https://sid.ir/paper/258104/en

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