EFFECT OF SODIUM-POTASSIUM INTAKE ON ARTERIAL STIFFNESS

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GOLSHAHI J.; MOBADI Z.; ZAMANI N.

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Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2001 | Volume:5 | Issue:4 Page(s): 328-330

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Title

EFFECT OF SODIUM-POTASSIUM INTAKE ON ARTERIAL STIFFNESS

Author(s)

GOLSHAHI J. | MOBADI Z. | ZAMANI N. | Issue Writer Certificate

Keywords

DIET THERAPYQ3

HYPERTENSIONQ4

ARTERIAL STIFFNESSQ4

ELECTROLYTEQ3

SODIUMQ3

POTASSIUMQ3

Abstract

Introduction. HYPERTENSION is one of the most common causes of cardiovascular problems in our society. Diet is the cheapest and the most accessible method of blood pressure (BP) control. BP is associated with ARTERIAL STIFFNESS which affects cardiac afterload. This study evaluate the effect of diertary Na and K on vascular compliance.Methods. We selected ninty six patients referred to Isfahan cardovascular Research center (affiliated to IUMSHS). Inclusion criteria were mild HYPERTENSION (90 <OBP< 99 mmHg and/or 140 <S.BP< 160 mmHg), age between 35-65 years old, body mass index (BMI) between 20-25, and no existing of any other chronic disease or medications. We divided samples into three equal diet group, randomly (A, B, G). The dietary content of SODIUM and POTASSIUM in each group was described as: moderate Na restriction + normal K content (group A), moderate Na restriction +high K content (group B), normal Na content + high K content (group G). Regimen was followed by each group for 16 weeks. Physical examination and anthropometric paramaters, lab data (e.g. FBS, Lipid profile, Uric acid, Serum Na & K, BUN, Gr and Ga), 24 hours urine sample for Na & K were compared before and after of intervention. In echocardiography the left ventricle dimensions and stroke volume were determined. Stroke volume: pulse pressure ratio was assumed as vascular compliance (1: ARTERIAL STIFFNESS).Results. Measured indicies were changed in groups as follow. Group A: Δ SBP = -8.43 mmHg; Δ DBP= -5.03 mmHg; Δ SV:PP= -0.28 ml/mmHg per beat (P> 0.05). Group B: Δ SBP= -0.82 mmHg; Δ OBP= -7.09 mmHg; Δ SV/PP= -0.22 ml/mmHg per beat (P> 0.05). Group G: Δ SBP=-7.22 mmHg; Δ OBP= -4.63 mmHg; Δ SV/PP= -0.01 ml/mmHg per beat (P>0.05).Discussion. We recommend the above diets specially type B, as the first step in the treatment approach of mild HTN in our society. These dietary modifications didn't have any effect on ARTERIAL STIFFNESS in 16 weeks of follow up. It is may be necessary to continue this intervention for changing ARTERIAL STIFFNESS.

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APA: Copy

GOLSHAHI, J., MOBADI, Z., & ZAMANI, N.. (2001). EFFECT OF SODIUM-POTASSIUM INTAKE ON ARTERIAL STIFFNESS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 5(4), 328-330. SID. https://sid.ir/paper/26566/en

Vancouver: Copy

GOLSHAHI J., MOBADI Z., ZAMANI N.. EFFECT OF SODIUM-POTASSIUM INTAKE ON ARTERIAL STIFFNESS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2001;5(4):328-330. Available from: https://sid.ir/paper/26566/en

IEEE: Copy

J. GOLSHAHI, Z. MOBADI, and N. ZAMANI, “EFFECT OF SODIUM-POTASSIUM INTAKE ON ARTERIAL STIFFNESS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 5, no. 4, pp. 328–330, 2001, [Online]. Available: https://sid.ir/paper/26566/en

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